The Incidence, Distribution and Significance of Megakaryocytes in Normal and Diseased Human Tissues [PDF]
Edward Smith, James Butcher
openalex +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
Variability in the Log Domain and Limitations to Its Approximation by the Normal Distribution. [PDF]
Elassaiss-Schaap J, Duisters K.
europepmc +1 more source
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
wiley +1 more source
The Distribution of "Student's" Ratio for Samples of Two Items Drawn from Non-Normal Universes [PDF]
Jack Laderman
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Normal distribution of bad reduction. [PDF]
Lemke Oliver RJ, Loughran D, Shnidman A.
europepmc +1 more source
Modeling observations with a detection limit using a truncated normal distribution with censoring. [PDF]
Williams JR, Kim HW, Crespi CM.
europepmc +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source
The Distribution of Cardiac Potentials Around the Chest in One Hundred and Three Normal Men [PDF]
Ernst Simonson
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Obtaining a Bayesian Estimate of Coefficient Alpha Using a Posterior Normal Distribution. [PDF]
DelosReyes JMV, Padilla MA.
europepmc +1 more source