TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Approximate Formulas for the Radii of Circles which Include a Specified Fraction of a Normal Bivariate Distribution [PDF]
, 1947 E. N. Oberg
openalex +1 more source
A near normal distribution of IQ in Fragile X Syndrome. [PDF]
Sci RepSchmitt LM +3 more
europepmc +1 more source
Expectation and variance of the estimator of the maximized selection response of linear selection indices with normal distribution. [PDF]
Theor Appl Genet, 2020 Cerón-Rojas JJ, Crossa J.
europepmc +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Some Significance Tests for Normal Bivariate Distributions [PDF]
, 1943 D. S. Villars, T. W. Anderson
openalex +1 more source
The Emergence of the Normal Distribution in Deterministic Chaotic Maps. [PDF]
Entropy (Basel)Zanette DH, Samengo I.
europepmc +1 more source
The accumulative law and its probability model: an extension of the Pareto distribution and the log-normal distribution. [PDF]
Proc Math Phys Eng Sci, 2020 Feng M +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
A property of the normal distribution related to a theorem of S. Bernstein
, 1953 Eugene Lukács, E. P. King
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