Results 91 to 100 of about 62,824 (310)
Opposing shear senses in a subdetachment mylonite zone: Implications for core complex mechanics [PDF]
, 2010 Global studies of metamorphic core complexes and low‐angle detachment faults have highlighted a fundamental problem: Since detachments excise crustal section, the relationship between the mylonitic rocks in their footwalls and the brittle deformation in ...
Frances J. Cooper +9 more
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Analysis of fault networks and conjugate systems
, 2013 Faults networks exist over a range of scales and are important for understanding the brittle deformation and fluid transport processes within the Earth’s crust.
Nixon, Casey William
core
, 2006 Oblique rifting in the offshore Taupo Volcanic Zone, New Zealand, is expressed in widely distributed active normal faulting in the 20 km-wide Whakatane Graben.
Lamarche, G. +5 more
core +1 more source
Normal Fault Database_Lathrop.xlsx
, 2021 Global database of normal fault length and displacement with other geological factors such as host rock lithology, tectonic setting, and fault maturity (tab 1). Fault length and displacement through time for available fault is also shown (tab 2). Sources
Bailey Lathrop (11761682)
core +1 more source
INTERNAL STRUCTURE OF FAULT ZONES: SPATIAL AND TEMPORAL EVOLUTION STUDIES ON CLAY MODELS
Геодинамика и тектонофизика, 2015 Based on results obtained from experiments on clay models, it appeared possible to establish main regularities in the evolution of normal and strike-slip zones which structures are formed heterogeneously in time and space.
Konstantin Zh Seminsky
doaj +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Fault slip-rate variations during crustal-scale strain localisation, central Italy
, 2002 Rates of plate motion are generally uniform over 10–102 Myrs timescales. Faults between tectonic plates might, therefore, be expected to show temporally-uniform slip-rates if the same number of faults remain active. For an extending region of the Eurasia-
Morewood, NC +4 more
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Breaking up the hanging wall of a rift-border fault: The 2009 Karonga earthquakes, Malawi
The southern East African Rift has an unusually large seismogenic thickness (35–40 km), which is responsible for wide tilted basins and extremely long faults with the potential for M7-8 normal-faulting earthquakes.
Nissen, E. +4 more
core +1 more source