Results 71 to 80 of about 42,179 (263)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2014 In this paper, we applied the differential interferometric synthetic aperture radar (DInSAR) technique to investigate and measure surface displacements due to the Mw 5.3 (M1 5.2), June 21, 2013 earthquake, occurred north of the Apuan Alps (NW Italy), in ...
Salvatore Stramondo +8 more
doaj +1 more source
On the origin and hade of normal faults [PDF]
American Journal of Science, 1883 n ...
openaire +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Dueling dynamics of low-angle normal fault rupture with splay faulting and off-fault damage. [PDF]
Nat Commun, 2023 Biemiller J, Gabriel AA, Ulrich T.
europepmc +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Research on dynamic response characteristics of normal fault footwall working face and rock burst prevention technology under the influence of the gob area. [PDF]
Sci Rep, 2023 Tai L, Li C, Gu S, Yu X, Xu Z, Sun L.
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Study on the Evolution of Fault Permeability and the Retention of Coal (Rock) Pillar under the Mining Conditions of Thick Coal Seam in the Footwall of Large Normal Fault. [PDF]
ACS Omega, 2023 Yin H +8 more
europepmc +1 more source