Results 91 to 100 of about 2,502,460 (317)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Local dynamics of DDE with large delay in the vicinity of the self-similar cycle

open access: yesМоделирование и анализ информационных систем, 2010
We research the local dynamics of a complex differential equation with large delay in the vicinity of the self-similar cycle. The quasinormal forms method is used for a problem analysis.
D. V. Glazkov, S. A. Kaschenko
doaj  

Equivalence and normal forms of bilinear forms

open access: yesLinear Algebra and its Applications, 2014
We present an alternative account of the problem of classifying and finding normal forms for arbitrary bilinear forms. Beginning from basic results developed by Riehm, our solution to this problem hinges on the classification of indecomposable forms and in how uniquely they fit together to produce all other forms. We emphasize the use of split forms, i.
openaire   +3 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Dynamical properties of a model for the passive mode locking

open access: yesМоделирование и анализ информационных систем, 2011
We study the local dynamics of a model for the passive mode locking in semiconductor lasers. In critical cases special equations (normal forms) were built. The existence of multistability is shown.
I. S. Kashchenko
doaj  

Unconditional well-posedness for the periodic Boussinesq and Kawahara equations

open access: yesElectronic Research Archive
In this article, we obtain new results on the unconditional well-posedness for a pair of periodic nonlinear dispersive equations using an abstract framework introduced by Kishimoto.
Dan-Andrei Geba
doaj   +1 more source

The Andronov–Hopf Bifurcation in a Biophysical Model of the Belousov Reaction

open access: yesМоделирование и анализ информационных систем, 2018
We consider the problem of mathematical modeling of oxidation-reduction oscillatory chemical reactions based on the Belousov reaction mechanism. The process of the main components interaction in such a reaction can be interpreted by a “predator – prey ...
Vladimir E. Goryunov
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

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