Results 91 to 100 of about 7,422,401 (338)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Nonlinear Modal Decoupling of Multi-Oscillator Systems With Applications to Power Systems
IEEE Access, 2018 Many natural and manmade dynamical systems that are modeled as large nonlinear multi-oscillator systems like power systems are hard to analyze. For such systems, we propose a nonlinear modal decoupling (NMD) approach inversely constructing as many ...
Bin Wang, Kai Sun, Wei Kang
doaj +1 more source
Convergent normal form for real hypersurfaces at generic Levi degeneracy [PDF]
, 2014 We construct a complete convergent normal form for a real hypersurface in $\CC{N},\,N\geq 2$ at generic Levi degeneracy. This seems to be the first convergent normal form for a Levi-degenerate hypersurface.
Kossovskiy, Ilya, Zaitsev, Dmitri
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Stable Cycles and Tori of a System of Three and Four Diffusive Coupled Oscillators
Моделирование и анализ информационных систем, 2016 We consider chains of identical diffusive weakly coupled oscillation systems with different conditions on coupling on a chain bound. We suppose that every interacting oscillator undergoes Andronov–Hopf bifurcation, and the coefficient of coupling is ...
E. A. Marushkina
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Chains with Connections of Diffusion and Advective Types
MathematicsThe local dynamics of a system of oscillators with a large number of elements and with diffusive- and advective-type couplings containing a large delay are studied.
Sergey Kashchenko
doaj +1 more source
Parametric Resonance in the Logistic Equation with Delay under a Two-Frequency Perturbation
Моделирование и анализ информационных систем, 2013 A logistic equation with a delay feedback circuit and with periodic perturbation of parameters is considered. The problem parameters (a coefficient of the linear growth and a delay) are chosen close to the critical values at which a cycle is bifurcated ...
N. D. Bykova +2 more
doaj +1 more source