Results 81 to 90 of about 18,139,107 (303)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
On greibach normal form construction
Theoretical Computer Science, 1985 In this note we present a procedure to rewrite a given Chomsky normal form grammar in Greibach normal form. This procedure yields the same grammar as the well-known procedure of Rosenkrantz, but is based on pure derivation-oriented reasoning and not on systems of equations.
openaire +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Comparison of metaheuristics for obtaining fuzzy predicates: a curious case
Revista Cubana de Ciencias Informáticas, 2014 This paper presents a comparative study of three metaheuristics on the problem of obtaining fuzzy predicates with high truth value. According to the No Free Lunch Theorem (NFL) cannot establish any general superiority of ...
Taymi Ceruto-Cordovés +3 more
doaj
Quality measures for fuzzy predicates in conjunctive and disjunctive normal forms
Ingeniería e Investigación, 2014 Association rule mining is a very popular data mining technique. Rules in this technique are often used to identify and represent de-pendencies between attributes in databases.
Taymi Ceruto Cordovés +2 more
doaj +1 more source
Poincaré Normal and Renormalized Forms
Acta Applicandae Mathematica, 2002 standard LaTeX, 20 ...
openaire +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Normal Forms in Combinatory Logic
Notre Dame Journal of Formal Logic, 1994 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source