Results 91 to 100 of about 4,146,228 (289)

Quality measures for fuzzy predicates in conjunctive and disjunctive normal forms

open access: yesIngeniería e Investigación, 2014
Association rule mining is a very popular data mining technique. Rules in this technique are often used to identify and represent de-pendencies between attributes in databases.
Taymi Ceruto Cordovés   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Comparison of metaheuristics for obtaining fuzzy predicates: a curious case

open access: yesRevista Cubana de Ciencias Informáticas, 2014
This paper presents a comparative study of three metaheuristics on the problem of obtaining fuzzy predicates with high truth value. According to the No Free Lunch Theorem (NFL) cannot establish any general superiority of ...
Taymi Ceruto-Cordovés   +3 more
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Normal Forms of the Degenerate Differential Autonomous and Non Autonomous Equations with the Maximal Jordan Chain of Length Two and Three

open access: yesИзвестия Иркутского государственного университета: Серия "Математика", 2015
Standard methods of normal form construction are adapted for degenerate differential equations in the case of the existence of maximal length Jordan chain. For n=2 and 3 examples are considered.
B.V. Loginov   +2 more
doaj  

Normal forms of piecewise-smooth monodromic systems

open access: yesAdvances in Nonlinear Analysis
Normal form is an important tool in the study of bifurcations but, unlike those for smooth differential systems, normal forms for piecewise-smooth systems have difficulty with the near-identity transformation, which is constructed piecewise but needs to ...
Li Jiahao, Chen Xingwu, Zhang Weinian
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Normal and Reverse Flow Injection Analysis Methods for Estimation of Mesalazine in Pharmaceutical Dosage Forms

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences, 2023
Determining the actual amounts of active ingredients in various pharmaceutical commercial forms is still receiving a lot of attention. Two flow injection analysis (FIA) methods were suggested for determination of mesalazine (MES) in pharmaceutical forms.
Bayan hasan, Hind Hadi
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy