Results 111 to 120 of about 18,139,107 (303)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Orbital Normal Forms for a family of-zero Singularity
پژوهشهای ریاضی, 2016 Consider a Dynamical system x'=F(x,µ) such that its linear part has a pair of imaginary eigenvalues and one zero eigenvalue (Hopf zero singularity). Recently, the simplest normal form for this singular system has been obtained by sl(2) Lie algebra theory
M Gazor, N Sadri
doaj
Contributions to Logical Database Design [PDF]
Informatică economică, 2012 This paper treats the problems arising at the stage of logical database design. It comprises a synthesis of the most common inference models of functional dependencies, deals with the problems of building covers for sets of functional dependencies, makes
Vitalie COTELEA
doaj
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Normal forms of dispersive scalar Poisson brackets with two independent variables. [PDF]
Lett Math Phys, 2018 Carlet G, Casati M, Shadrin S.
europepmc +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Normal forms for Poisson maps and symplectic groupoids around Poisson transversals. [PDF]
Lett Math Phys, 2018 Frejlich P, Mărcuț I.
europepmc +1 more source