Results 81 to 90 of about 84,144,549 (259)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

A remark on normal forms of matrices [PDF]

open access: yes, 1980
Dlab V, Ringel CM. A remark on normal forms of matrices. Linear algebra and its applications.
Dlab, Vlastimil, Ringel, Claus Michael
core   +1 more source

Computation of the Unique Normal Form for Nonlinear Dynamical Systems in the Mechanical Applications

open access: yesDEStech Transactions on Engineering and Technology Research, 2017
In the mechanical applications, research for degenerate bifurcations is usually connected with the normal form theory of nonlinear dynamical systems. In this paper, we mainly concern with the unique normal form for a class of three dimensional vector fields by the method of transformation with parameters. With the aid of the Maple software, a recursive
Li-ying KOU, Jing LI, Jian-pan FENG
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Specific impairments in cognitive development: a dynamical systems approach [PDF]

open access: yes, 2008
Neuropsychologists have frequently proposed that domain-specific deficits can be observed in developmental disorders (e.g., phonology in dyslexia, theory of mind in autism, grammar in specific language impairment, face recognition in prosopagnosia ...
Baughman, Frank D., Thomas, Michael S.C.
core  

Conjugacy of Dynamical Systems on Self-Similar Groups

open access: yes, 2020
We show that the limits for dynamical systems of self-similar groups are eventually conjugate if, and only if, there is an isomorphism between their Deaconu groupoid preserving cocycles.
Inhyeop Yi
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Numerical analysis of dynamical systems with codimension two singularities [PDF]

open access: yes, 2009
Páez Chávez JN. Numerical analysis of dynamical systems with codimension two singularities.
Páez Chávez, Joseph Nikolai
core  

Computer algebra derives normal forms of stochastic differential equations [PDF]

open access: yes, 2007
Modelling stochastic systems has many important applications. Normal form coordinate transforms are a powerful way to untangle interesting long term dynamics from undesirably detailed microscale dynamics.
Roberts, A. J.
core   +1 more source

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