Results 51 to 60 of about 744,325 (256)

Thermo-Bioconvection in Nanoliquid Suspension Saturated with Thermotactic Microorganisms

open access: yesForces in Mechanics, 2022
This study primarily focuses on the analytical investigation of thermal-bioconvection in the nanoliquid layer confined between two horizontal parallel walls. Bioconvection is considered to be driven by thermotactic microorganisms.
Ankita Bisht, Sanjalee Maheshwari
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Thermoelastic Interaction in a Three-Dimensional Layered Sandwich Structure [PDF]

open access: yesMechanics of Advanced Composite Structures, 2018
The present article investigates the thermoelastic interaction in a three-dimensional homogeneous and isotropic sandwich structure using the dual-phase-lag (DPL) model of generalized thermoelasticity.
Abhik Sur, M. Kanoria
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Effect of Rotation in an Orthotropic Elastic Slab

open access: yesInternational Journal of Applied Mechanics and Engineering, 2017
The fundamental equations of the two dimensional generalized thermoelasticity (L-S model) with one relaxation time parameter in orthotropic elastic slab has been considered under effect of rotation. The normal mode analysis is used to the basic equations
S. Santra, A. Lahiri, N.C. Das
doaj   +1 more source

In-silico phenotype prediction by normal mode variant analysis in TUBB4A-related disease

open access: yesScientific Reports, 2022
TUBB4A-associated disorder is a rare condition affecting the central nervous system. It displays a wide phenotypic spectrum, ranging from isolated late-onset torsion dystonia to a severe early-onset disease with developmental delay, neurological deficits,
Avi Fellner   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Coarse-grained normal mode analysis in structural biology [PDF]

open access: yesCurrent Opinion in Structural Biology, 2005
The realization that experimentally observed functional motions of proteins can be predicted by coarse-grained normal mode analysis has renewed interest in applications to structural biology. Notable applications include the prediction of biologically relevant motions of proteins and supramolecular structures driven by their structure-encoded ...
Ivet, Bahar, A J, Rader
openaire   +2 more sources

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