Results 31 to 40 of about 744,325 (256)

Structure and Function of the Human Ryanodine Receptors and Their Association with Myopathies—Present State, Challenges, and Perspectives

Molecules, 2020
Cardiac arrhythmias are serious, life-threatening diseases associated with the dysregulation of Ca2+ influx into the cytoplasm of cardiomyocytes. This dysregulation often arises from dysfunction of ryanodine receptor 2 (RyR2), the principal Ca2+ release ...
Vladena Bauerová-Hlinková, Dominika Hajdúchová, Jacob A. Bauer   +2 more
doaj   +1 more source

Fractional Order Thermoelastic Model with Voids in Three-Phase-Lag Thermoelasticity

Computer Sciences & Mathematics Forum, 2023
This paper deals with fractional order three-phase-lag (TPL) thermo-elasticity in a micropolar thermoelastic half space medium with voids. The subsequent non-dimensional coupled equations are solved by using the normal mode analysis and eigenvalue ...
Sourov Roy, Abhijit Lahiri
doaj   +1 more source

Normal Mode Analysis of Na2O 3SiO2 Glass

Physics Procedia, 2013
AbstractThe work aims at the modelling of molecular spectra of complicated oxide glasses by the ab initio molecular dynamics. As a first step, a classical molecular dynamics simulation of Na2O·3SiO2 silicate glass has been performed to obtain a model of a rather simple glass structure in which some simulation size effects can be evaluated.
Machacek, Jan, Gedeon, Ondrej, Liska, Marek   +2 more
openaire   +1 more source

Novel RyR2 Mutation (G3118R) Is Associated With Autosomal Recessive Ventricular Fibrillation and Sudden Death: Clinical, Functional, and Computational Analysis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background The cardiac ryanodine receptor type 2 (RyR2) is a large homotetramer, located in the sarcoplasmic reticulum (SR), which releases Ca2+ from the SR during systole. The molecular mechanism underlying Ca2+ sensing and gating of the RyR2 channel in
Ayelet Shauer, Oded Shor, Jinhong Wei, Yair Elitzur, Nataly Kucherenko, Ruiwu Wang, S. R. Wayne Chen, Yulia Einav, David Luria   +8 more
doaj   +1 more source

Harmonic waves solution in dual-phase-lag magneto-thermoelasticity

Open Physics, 2019
The current work analyzes the transmission behavior of plane harmonic waves in an isotropic medium. The observation is made for homogeneous type solid in the context of generalized dual phase lag model of thermoelasticity.
Rafiq Muhammad, Singh Baljeet, Arifa Samreen, Nazeer Muhammad, Usman Muhammad, Arif Shoaib, Bibi Mairaj, Jahangir Adnan   +7 more
doaj   +1 more source

Study of Thermoelectric Responses of a Conductive Semi-Solid Surface to Variable Thermal Shock in the Context of the Moore–Gibson–Thompson Thermoelasticity

Axioms, 2023
In this study, the Moore–Gibson–Thompson (MGT) concept of thermal conductivity is applied to a two-dimensional elastic solid in the form of a half-space.
Sami F. Megahid, Ahmed E. Abouelregal, Sameh S. Askar, Marin Marin   +3 more
doaj   +1 more source

A two dimensional fibre reinforced micropolar thermoelastic problem for a half-space subjected to mechanical force [PDF]

Theoretical and Applied Mechanics, 2015
The purpose of this paper is to study the two dimensional deformation of fibre reinforced micropolar thermoelastic medium in the context of Green-Lindsay theory of thermoelasticity. A mechanical force is applied along the interface of fluid half
Ailawalia Praveen, Sachdeva Sunil Kumar, Pathania Devinder   +2 more
doaj   +1 more source

In Search of a Dynamical Vocabulary: A Pipeline to Construct a Basis of Shared Traits in Large-Scale Motions of Proteins

Applied Sciences, 2022
The paradigmatic sequence–structure–dynamics–function relation in proteins is currently well established in the scientific community; in particular, a large effort has been made to probe the first connection, indeed providing convincing evidence of its ...
Thomas Tarenzi, Giovanni Mattiotti, Marta Rigoli, Raffaello Potestio   +3 more
doaj   +1 more source

Elasto-Thermodiffusive Response in a Two-Dimensional Transversely Isotropic Medium [PDF]

Mechanics of Advanced Composite Structures, 2019
The present article investigates the elasto-thermodiffusive interactions in a transversely isotropic elastic medium in the context of thermoelasticity with one relaxation time parameter and two relation time parameters.
Abhik Sur, M. Kanoria
doaj   +1 more source

Site Density Functional Theory and Structural Bioinformatics Analysis of the SARS-CoV Spike Protein and hACE2 Complex

Molecules, 2022
The entry of the SARS-CoV-2, a causative agent of COVID-19, into human host cells is mediated by the SARS-CoV-2 spike (S) glycoprotein, which critically depends on the formation of complexes involving the spike protein receptor-binding domain (RBD) and ...
Nitesh Kumawat, Andrejs Tucs, Soumen Bera, Gennady N. Chuev, Marat Valiev, Marina V. Fedotova, Sergey E. Kruchinin, Koji Tsuda, Adnan Sljoka, Amit Chakraborty   +9 more
doaj   +1 more source