Results 41 to 50 of about 267,527 (261)

Normalizing Normal Mode Analysis [PDF]

Structure, 2007
A detailed understanding of protein dynamics remains elusive. Recent comparisons of computer simulations with experimental data are calibrating the methods and establishing their applications. In this issue of Structure, Kondrashov et al. (2007) exemplify the approach by comparing computed normal modes with measured crystallographic B factors.
openaire   +1 more source

Measurable Residual Disease Monitoring During Treatment for Pediatric Acute Myeloid Leukemia in First Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survival after relapse in pediatric acute myeloid leukemia (AML) remains poor, highlighting the critical importance of identifying prognostic factors to guide optimal relapse management. Methods We investigated the prognostic impact of multiparameter flow cytometry (MFC) measurable residual disease (MRD) in 188 patients with first ...
Camilla Poulsen, Kristian Juul Sandahl, Lene Karlsson, Jonas Abrahamsson, Nira Arad‐Cohen, Daniel Cheuk, Barbara De Moerloose, Linda Fogelstrand, Jose Maria Fernandez Navarro, Bianca F. Goemans, Kirsi Jahnukainen, Gertjan Kaspers, Zhanna Kovalova, Monica Cheng Munthe‐Kaas, Ulrika Norén‐Nyström, Josefine Palle, Ramune Pasauliene, Cornelis Jan Pronk, Kadri Saks, Anne Tierens, Henrik Hasle, Kristian Løvvik Juul‐Dam   +21 more
wiley   +1 more source

Structural Dynamics of DPP-4 and Its Influence on the Projection of Bioactive Ligands

Molecules, 2018
Dipeptidyl peptidase-4 (DPP-4) is a target to treat type II diabetes mellitus. Therefore, it is important to understand the structural aspects of this enzyme and its interaction with drug candidates.
Simone Queiroz Pantaleão, Eric Allison Philot, Pedro Túlio de Resende-Lara, Angélica Nakagawa Lima, David Perahia, Maria Atanassova Miteva, Ana Ligia Scott, Kathia Maria Honorio   +7 more
doaj   +1 more source

Wavenumber-Frequency Spectra of Normal Mode Function Decomposed Atmospheric Data: Departures from the Dry Linear Theory

Atmosphere, 2023
The study of tropical tropospheric disturbances has led to important challenges from both observational and theoretical points of view. In particular, the observed wavenumber-frequency spectrum of tropical oscillations has helped bridge the gap between ...
Andre S. W. Teruya, Breno Raphaldini, Victor C. Mayta, Carlos F. M. Raupp, Pedro L. da Silva Dias   +4 more
doaj   +1 more source

Bridging the Gap in Neuroblastoma Care: Consensus‐Based Statements With Recommendations for Improved Patient and Caregiver Experiences

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neuroblastoma's complex, heterogeneous biology poses significant diagnostic and therapeutic challenges, often requiring caregivers to absorb complex information and participate in time‐sensitive decisions. However, caregivers often feel unprepared to evaluate options.
Vickie Buenger, Joseph Bauer, Jennifer Diamond, Maggie Fader, Shae Hansen, Jacqueline M. Kraveka, Johanna Schoen, Amber Shearer, Dena Sherwood   +8 more
wiley   +1 more source

Analysis of Neutron Star f-mode Oscillations in General Relativity with Spectral Representation of Nuclear Equations of State

The Astrophysical Journal
We study quasi-normal f -mode oscillations in neutron star (NS) interiors within a linearized general relativistic formalism. We utilize approximately 9000 nuclear equations of state (EOSs) using spectral representation techniques, incorporating ...
Debanjan Guha Roy, Tuhin Malik, Swastik Bhattacharya, Sarmistha Banik   +3 more
doaj   +1 more source

Impact of Metastatic Patterns on Survival and Response to Therapy in Neuroblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background While the presence of metastases in neuroblastoma (NB) is a well‐established prognostic factor, the clinical significance of dissemination patterns and tumour burden and their impact on response and survival remains poorly understood.
Mariona Morell‐Daniel, Santiago Pérez‐Hoyos, Aroa Soriano, Ana Coma, Amalia Varo, Raquel Hladun, Gabriela Guillén, Soraya Mico, Marta Garrido, Lourdes Rubio, Alba Rubio‐San‐Simón, Ana Minguez, Ricardo López‐Almaraz, Laura Illade, Miguel F. Segura, Lucas Moreno   +15 more
wiley   +1 more source

Animal‐Assisted Activities With Therapy Dogs in Pediatric Oncology: A Multicenter Survey of the Current Status, Implementation, and Challenges in Germany, Austria, and Switzerland

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Animal‐assisted activities (AAAs) with therapy dogs have shown positive effects on patient well‐being and quality of life in various areas of medicine, including pediatric oncology. However, research on this topic is limited. The aim of this study is to present the current status of AAA in pediatric oncology in Germany, Austria, and
Jan‐Marius Wedig, Birgit Burkhardt, Christof M. Kramm, Kira Ostermann, Sarah C. Goretzki, Uta Dirksen, Nico Kurpiers, Michael M. Schündeln   +7 more
wiley   +1 more source

Computational analysis of vibrational spectrum and hydrogen bonds of ice XVII

New Journal of Physics, 2019
Based on first-principles density functional theory, we investigated the relationship between the vibrational normal modes and the spectrum of the newest laboratory-prepared ice phase, an empty clathrate hydrate structure from gas hydrate named ice XVII.
Xu-Liang Zhu, Zhen-Yu Yuan, Lu Jiang, Kai Zhang, Ze-Ren Wang, Hui-Wen Luo, Yue Gu, Jing-Wen Cao, Xiao-Ling Qin, Peng Zhang   +9 more
doaj   +1 more source

Coupled-Mode Parabolic Equations for the Modeling of Sound Propagation in a Shallow-Water Waveguide with Weak Elastic Bottom

Journal of Marine Science and Engineering, 2022
In this work, a mode parabolic equation method with interacting modes accounting for the weak elasticity at the bottom is developed. An important feature of the proposed method is that computations of elastic modes are avoided and that the solution is ...
Sergey Kozitskiy
doaj   +1 more source