Results 51 to 60 of about 3,724,631 (298)

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Hydrodynamical normal mode estimation on the INTIFANTE'00 data set [PDF]

, 2001
Rep 04/01 - SiPLAB 23/November/2001This report introduces a theoretical description of Dynamic Normal Modes, their relationship to temperature, salinity, and sound speed perturbations, and also of the numerical methods that allow the calculation of ...
Rodríguez, O. C.
core  

Analysis of Neutron Star f-mode Oscillations in General Relativity with Spectral Representation of Nuclear Equations of State

The Astrophysical Journal
We study quasi-normal f -mode oscillations in neutron star (NS) interiors within a linearized general relativistic formalism. We utilize approximately 9000 nuclear equations of state (EOSs) using spectral representation techniques, incorporating ...
Debanjan Guha Roy, Tuhin Malik, Swastik Bhattacharya, Sarmistha Banik   +3 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Structural Dynamics of DPP-4 and Its Influence on the Projection of Bioactive Ligands

Molecules, 2018
Dipeptidyl peptidase-4 (DPP-4) is a target to treat type II diabetes mellitus. Therefore, it is important to understand the structural aspects of this enzyme and its interaction with drug candidates.
Simone Queiroz Pantaleão, Eric Allison Philot, Pedro Túlio de Resende-Lara, Angélica Nakagawa Lima, David Perahia, Maria Atanassova Miteva, Ana Ligia Scott, Kathia Maria Honorio   +7 more
doaj   +1 more source

Wavenumber-Frequency Spectra of Normal Mode Function Decomposed Atmospheric Data: Departures from the Dry Linear Theory

Atmosphere, 2023
The study of tropical tropospheric disturbances has led to important challenges from both observational and theoretical points of view. In particular, the observed wavenumber-frequency spectrum of tropical oscillations has helped bridge the gap between ...
Andre S. W. Teruya, Breno Raphaldini, Victor C. Mayta, Carlos F. M. Raupp, Pedro L. da Silva Dias   +4 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Dependence of normal modes of the barotropic vortex equation on the mean flow structure and numerical simulation parameters

Solar-Terrestrial Physics
We present the results of numerical simulations of normal modes of the mean flow due to the superposition of cyclonic and anticyclonic vortices at high latitudes.
Mordvinov V. I., Devyatova E. V., Tomozov V. M.   +2 more
doaj   +1 more source