Results 71 to 80 of about 3,724,631 (298)
, 1997 A linearized perturbation about the Vialov-Nye fixed-span solution for a steady-state ice sheet yields a Sturm-Liouville problem. The numerical eigenvalue problem is solved and the resulting normal modes are used to compute Green's and influence ...
Hindmarsh, Richard C.A.
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Quasi-normal modes and fermionic vacuum decay around a Kerr black hole [PDF]
, 2019 We analyze the instability of the non-rotating fermion vacuum in Kerr spacetimes. We describe how the co-rotating Fermi sea is formed as a result of a spontaneous vacuum decay.
Millington, P; id_orcid +3 more
core +1 more source
On the Probability Density of the Nuclei in a Vibrationally Excited Molecule
Frontiers in Chemistry, 2019 For localized and oriented vibrationally excited molecules, the qualitative features of the one-body probability density of the nuclei (one-nucleus density) are investigated.
Axel Schild
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Development of a normal mode-based geometric simulation approach for investigating the intrinsic mobility of proteins [PDF]
, 2010 Specific functions of biological systems often require conformational transitions of macromolecules. Thus, being able to describe and predict conformational changes of biological macromolecules is not only important for understanding their impact on ...
Ahmed, Aqeel
core
Flutter calculation based on gvt-results and theoretical mass model
Aviation, 2009 Ground vibration tests (GVT) are a typical source of data for flutter prediction. In this paper, a simple, lowcost method to calculate flutter is presented.
Wojciech Chajec
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source