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Maternal Immunological Adaptation During Normal Pregnancy

open access: yesFrontiers in Immunology, 2020
The risk and severity of specific infections are increased during pregnancy due to a combination of physiological and immunological changes. Characterizing the maternal immune system during pregnancy is important to understand how the maternal immune ...
Bahaa Abu-Raya   +13 more
doaj   +2 more sources

Normal Pregnancy- A State of Insulin Resistance [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
Background: Purpose of insulin resistance (IR) adapted by mother is to deliver enough quantity of nutrients to the growing fetus. Many maternal hormones and factors play role in causation of IR during pregnancy.
Amit D. Sonagra   +3 more
doaj   +2 more sources

M2 macrophage‐derived G‐CSF promotes trophoblasts EMT, invasion and migration via activating PI3K/Akt/Erk1/2 pathway to mediate normal pregnancy

open access: yesJournal of Cellular and Molecular Medicine, 2021
Trophoblasts are important parts of the placenta and exert vital roles in the maternal‐foetal crosstalk, and sufficient trophoblasts migration and invasion is critical for embryo implantation and normal pregnancy.
Jinli Ding   +7 more
semanticscholar   +1 more source

Oxidative stress: Normal pregnancy versus preeclampsia.

open access: yesBiochimica et Biophysica Acta - Molecular Basis of Disease, 2020
The role of oxidative stress in the physiopathology of human pregnancy is of particular interest. Pregnancy is well-known to increase the oxidative stress, mainly produced by a normal systemic inflammatory response, which results in high amounts of ...
D. Chiarello   +7 more
semanticscholar   +1 more source

Extracellular vesicles in normal pregnancy and pregnancy‐related diseases

open access: yesJournal of Cellular and Molecular Medicine, 2020
Extracellular vesicles (EVs) are nanosized, membranous vesicles released by almost all types of cells. Extracellular vesicles can be classified into distinct subtypes according to their sizes, origins and functions.
Jiayin Zhang   +4 more
semanticscholar   +1 more source

Insight Into TLR4-Mediated Immunomodulation in Normal Pregnancy and Related Disorders

open access: yesFrontiers in Immunology, 2020
Unlike organ transplants where an immunosuppressive environment is required, a successful pregnancy involves an extremely robust, dynamic, and responsive maternal immune system to maintain the development of the fetus.
P. Firmal   +2 more
semanticscholar   +1 more source

Obesity Challenge Drives Distinct Maternal Immune Response Changes in Normal Pregnant and Abortion-Prone Mouse Models

open access: yesFrontiers in Immunology, 2021
Obesity is prevalent among women of reproductive age and is associated with increased risk of developing multiple pregnancy disorders. Pregnancy must induce immune tolerance to avoid fetal rejection, while obesity can cause chronic inflammation through ...
Yanhong Li   +7 more
doaj   +1 more source

Maternal obesity is associated with the formation of small dense LDL and hypoadiponectinemia in the third trimester [PDF]

open access: yes, 2013
Context: Maternal obesity is associated with high plasma triglyceride, poor vascular function, and an increased risk for pregnancy complications. In normal-weight pregnant women, higher triglyceride is associated with increased small, dense low-density ...
Brown, E.A.   +9 more
core   +2 more sources

Spontaneous Ovarian Hyperstimulation Syndrome in a Normal Singleton Pregnancy

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2006
Objective: It is known that most cases of ovarian hyperstimulation syndrome (OHSS) are associated with the therapies for ovulation induction. However, OHSS may rarely be associated with a spontaneous ovulatory cycle, usually in the case of multiple ...
Ozer Oztekin, Ferit Soylu, Orkan Tatli
doaj   +1 more source

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