Results 71 to 80 of about 798,154 (283)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Normalizers and self-normalizing subgroups
Glasnik matematicki, 2011 Let $\mathbb K$ be a field of characteristic $\neq 2$. Suppose $G=\boldsymbol{; ; G}; ; (\mathbb K)$ is the group of $\mathbb K$-points of a reductive algebraic $\mathbb K$-group $\boldsymbol{; ; G}; ; $. Let $G_1\leq G$ be the group of $\mathbb K$-points of a reductive subgroup $\boldsymbol{; ; G}; ; _1\leq \boldsymbol{; ; G}; ; $.
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Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Products of Normal Supersolvable Subgroups [PDF]
Proceedings of the American Mathematical Society, 1971 It is shown in this paper that if G is a finite group which is the product of two normal supersolvable subgroups of relatively prime index, then G is supersolvable.
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FEBS Open Bio, EarlyView.We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan +6 more
wiley +1 more source
Algebraic Characteristics of Anti-Intuitionistic Fuzzy Subgroups Over a Certain Averaging Operator
IEEE Access, 2020 In this paper, we propose the concept of ρ anti-intuitionistic fuzzy sets, ρ anti - intuitionistic fuzzy subgroups and prove some of their algebraic properties.
Dilshad Alghazzawi +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
A New Constrain Group Operating on Neutrosophic Fuzzy Subgroup and Normal Subgroup [PDF]
Neutrosophic Sets and SystemsThis research presents an innovative concept known as the Neutrosophic group operating on fuzzy subsets, extending the traditional algebraic framework to include elements of fuzziness and neutrosophy.
M. Premkumar +7 more
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