Results 201 to 210 of about 526,031 (267)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Enhancing genomic selection for reproductive traits in turkeys through SNP prioritization using the fixation index. [PDF]

Poult Sci
Hartono E, Willems OW, Bai X, Wood BJ, Toghiani S, Rekaya R, Aggrey SE.   +6 more
europepmc   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

The recombinant IL-35 and anti-Ebi3 antibody administration before implantation modulate immune regulation and fetal outcomes in an abortion-prone mouse model. [PDF]

Front Immunol
Slawek A, Kubik P, Psurski M, Kedzierska AE, Chelmonska-Soyta A.   +4 more
europepmc   +1 more source

Testing the Normality of Residuals on Regression Model for the Growth of Paracoccus sp. SKG on Acetonitrile

, 2015
Mohd Izuan Effendi Halmi, M.S. Shukor, Noor Azlina Masdor, Nor Aripin Shamaan, Mohd Khalizan Sabullah, Mohd Yunus Shukor   +5 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Multidimensional analysis of clinical pharmacist intervention impact on hospital length of stay in pulmonary tuberculosis: a random forest-driven retrospective study. [PDF]

BMC Infect Dis
Wang R, Liu H, Zhang Y, Lei Q, Li T, Zheng Y.   +5 more
europepmc   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Effects of 8 weeks of moderate physical training on body composition, lipid profile, inflammatory markers, and physical activity in middle aged females. [PDF]

Front Endocrinol (Lausanne)
Sellami M, Almuraikhy S, Anwardeen N, Nizamuddin PB, Othman H, Alathba N, Alareer N, Elrayess MA.   +7 more
europepmc   +1 more source