Results 211 to 220 of about 751,319 (360)

A Psychiatrist Examines the Concept of Normality

, 1973
Offer, Daniel
core   +1 more source

Analysis of Bond Strength of Bioceramic Sealer Following Irrigation with Chlorhexidine. [PDF]

Iran Endod J
Costa LG, Saldanha JM, da Silva-Filho JE, Aguiar BA, de Almeida Gomes F, Gurgel-Filho ED.   +5 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

RibXcar with Dots Point Technique: The Science of Fracture as a Safety Principle. [PDF]

Plast Reconstr Surg Glob Open
Manzaneda Cipriani RM, Duran H, Adrianzen GA, Flores E, Romero Algara E, Salazar JD, Moussa HB, Fogel B, Chumbiauca Munares R, Gamarra Quispe GE.   +9 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Correction: When means and standard deviations are an incomplete summary of a continuous variable: problems, solutions, and utilising the reference ranges to check normality. [PDF]

BMJ Med
europepmc   +1 more source

Impact of Layer Thickness on Mechanical Properties and Surface Roughness of FDM-Printed Carbon Fiber-PEEK Composite. [PDF]

Materials (Basel)
Megersa GK, Sitek W, Nowak AJ, Krzemiński Ł, Kajzer W, Niewolik D.   +5 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

The Pursuit of the Minor Premise: A Commentary on Normality

, 1981
Murphy, Edmond A.
core   +1 more source

Comparing the Weighted Gain Score and a Rasch-Based Approach for Estimating Learning Outcomes in Medical Education: Quantitative Study. [PDF]

JMIR Med Educ
Aliyev R, Backhaus J, Hammer S, König S.   +3 more
europepmc   +1 more source