Results 191 to 200 of about 1,117,675 (339)

Clopidogrel Administration Impairs Neurovascular Unit Recovery and Exacerbates Amyloid Beta Accumulation in Aged Mice Post-Stroke. [PDF]

Int J Mol Sci
Paul M, Paul JW, Hinwood M, Hood RJ, Martin K, Abdolhoseini M, Johnson SJ, Pollack M, Nilsson M, Walker FR.   +9 more
europepmc   +1 more source

Testing bivariate independence and normality [PDF]

, 1997
W.C.M. Kallenberg, Teresa Ledwina, Ewaryst Rafajłowicz   +2 more
openalex  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Effectiveness of pelvic stabilization exercises on knee valgus, muscle activity, and strength in individuals with dynamic knee valgus. [PDF]

BMC Musculoskelet Disord
Ambrus M, Wolf G, Molnár D, Soussi B, Horváth T, Horváth M, Lacza Z.   +6 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Intracellular calcium release activates carotid body afferents by fentanyl. [PDF]

Function (Oxf)
Peng YJ, Kabil O, Wang N, Xie Z, Fox AP, Prabhakar NR.   +5 more
europepmc   +1 more source

Empirical power of F and normality tests under different experimental conditions

Homero Ribeiro Neto, Marciel Lelis Duarte, Nerílson Terra Santos   +2 more
openalex   +2 more sources

Asymptotics in multiple hypotheses testing under dependence: beyond normality [PDF]

Monitirtha Dey
openalex   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Secukinumab compared to ixekizumab in biologic-naïve Chinese individuals afflicted with moderate-to-severe plaque psoriasis: A retrospective single-center analysis. [PDF]

Medicine (Baltimore)
Zhao D.
europepmc   +1 more source