Results 161 to 170 of about 679,648 (296)

Association of Vitamin D Repletion with Normalization of Elevated Serum 17-OH-Progesterone [PDF]

, 2017
Gabriel Fenteany, Taiga Inoue, Gül Bahtiyar, Alan Sacerdote   +3 more
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

A dynamic spatiotemporal normalization model captures perceptual and neural effects of spatial and temporal context. [PDF]

PLoS Biol
Chapman AF, Denison RN.
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

The impact of pre-processing techniques on deep learning breast image segmentation. [PDF]

Sci Rep
Catarino J, Garcia NC, Silva S, Santinha J.   +3 more
europepmc   +1 more source

Optimal Design of the Adaptive Normalized Matched Filter Detector Using Regularized Tyler Estimators

, 2017
Abla Kammoun, Romain Couillet, Frédéric Pascal, Mohamed‐Slim Alouini   +3 more
openalex   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

LIMPACAT: Multi-omics attention transformer for immune prediction in liver cancer using whole-slide imaging. [PDF]

PLoS One
Chiu YJ.
europepmc   +1 more source

Increasing amounts of dietary fiber provided by foods normalizes physiologic response of the large bowel without altering calcium balance or fecal steroid excretion

, 1998
Valerie S. Haack, JOAN G. CHESTERS, Nicholas W. Vollendorf, Jon A. Story, Judith A. Marlett   +4 more
openalex   +1 more source

Existence and symmetry of normalized ground state to Choquard equation with local perturbation [PDF]

, 2021
Xinfu Li
openalex