Results 51 to 60 of about 418,008 (299)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
OCP Based Online Multisensor Data Fusion for Autonomous Ground Vehicle [PDF]
, 2010 In this paper, online multisensor data fusion algorithm using CORBA event channel is proposed, in order to deal with simplifying problem in sensor registration and fusion for vehicle’s state estimation.
Syahroni, Nanang
core
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Fast prediction of the performance of the centrifugal pump based on reduced-order model
Energy Reports, 2023 In the present paper, the prediction of the performance of a centrifugal pump is investigated based on proper orthogonal decomposition (POD) reduced-order model (ROM).
Zhiguo Wei +4 more
doaj +1 more source
Structural Equation Modeling: A Multidisciplinary JournalMultiple imputation (MI) is one of the recommended modern techniques for handling missing data in structural equation modeling (SEM) and evaluating model fit is a crucial aspect of analyzing SEM models. Methods for pooling model fit indices across imputed datasets are still under development, however, especially in the context of non-normal data.
Yunhang Yin +3 more
openaire +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Lithium-Ion Battery Capacity Prediction with GA-Optimized CNN, RNN, and BP
Applied SciencesOver the last 20 years, lithium-ion batteries have become widely used in many fields due to their advantages such as ease of use and low cost. However, there are concerns about the lifetime and reliability of these batteries.
Fatih Durmus, Serap Karagol
doaj +1 more source
Downlink Performance of Superimposed Pilots in Massive MIMO systems
, 2018 In this paper, we investigate the downlink throughput performance of a massive multiple-input multiple-output (MIMO) system that employs superimposed pilots for channel estimation.
Upadhya, Karthik +2 more
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Chaos Time Series Prediction Based on Membrane Optimization Algorithms
The Scientific World Journal, 2015 This paper puts forward a prediction model based on membrane computing optimization algorithm for chaos time series; the model optimizes simultaneously the parameters of phase space reconstruction (τ,m) and least squares support vector machine (LS-SVM ...
Meng Li +4 more
doaj +1 more source