Results 61 to 70 of about 418,008 (299)

Evaluation of precipitation simulations in CMIP6 models over Uganda

open access: yesInternational Journal of Climatology, 2021
This study employed 15 CMIP6 GCMs and evaluated their ability to simulate rainfall over Uganda during 1981–2014. The models and the ensemble mean were assessed based on the ability to reproduce the annual climatology, seasonal rainfall distribution and ...
Hamida Ngoma   +5 more
semanticscholar   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Energy Spectrum Extraction and Optimal Imaging via Dual-Energy Material Decomposition

open access: yes, 2015
Inferior soft-tissue contrast resolution is a major limitation of current CT scanners. The aim of the study is to improve the contrast resolution of CT scanners using dual-energy acquisition.
Niu, Tianye   +4 more
core   +1 more source

Evaluation of NASA POWER Reanalysis Products to Estimate Daily Weather Variables in a Hot Summer Mediterranean Climate

open access: yesAgronomy, 2021
This study aims to evaluate NASA POWER reanalysis products for daily surface maximum (Tmax) and minimum (Tmin) temperatures, solar radiation (Rs), relative humidity (RH) and wind speed (Ws) when compared with observed data from 14 distributed weather ...
G. Rodrigues, R. Braga
semanticscholar   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Accelerated Progression of Gait Impairment in Parkinson's Disease and REM Sleep Without Atonia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with Parkinson's disease (PD) and rapid eye movement (REM) sleep without atonia (RSWA) often have more severe gait disturbances compared to PD without RSWA. The association between the presence and expression of RSWA and the rate of progression of gait impairment in PD is unknown.
Sommer L. Amundsen‐Huffmaster   +11 more
wiley   +1 more source

Seasonal evaluation of downscaled land surface temperature: A case study in a humid tropical city

open access: yesHeliyon, 2019
The present study evaluates the seasonal variation of estimated error in downscaled land surface temperatures (LST) over a heterogeneous urban land.
Himanshu Govil   +3 more
doaj   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu   +11 more
wiley   +1 more source

Recommendation for Measuring Digital Volume Pulse in Mobile Application: For Healthy Normal Subject

open access: yesIEEE Access, 2021
The aim of this study was to identify changes in photoplethysmogram waveform with decreasing sampling frequency and quantization bit depth and suggest appropriate criteria for measurements.
Hyeon Seok Seok, Hangsik Shin
doaj   +1 more source

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