Results 91 to 100 of about 320,316 (300)

Normalized solutions of $L^2$-supercritical NLS equations on noncompact metric graphs with localized nonlinearities

open access: yes, 2023
In this paper we are concerned with the existence of normalized solutions for nonlinear Schr\"odinger equations on noncompact metric graphs with localized nonlinearities.
Jeanjean, L   +11 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

UV-VIS absorption (A) and normalized fluorescence (B) spectra of styrylquinolines solutions in DMSO.

open access: yes, 2015
UV-VIS absorption (A) and normalized fluorescence (B) spectra of styrylquinolines solutions in DMSO.
Wioleta Cieslik (761402)   +9 more
core   +1 more source

Normalized solutions for a Choquard equation with exponential growth in $\mathbb{R}^{2}$

open access: yes, 2022
In this paper, we study the existence of normalized solutions to the following nonlinear Choquard equation with exponential growth \begin{align*} \left\{ \begin{aligned} &-\Delta u+\lambda u=(I_{\alpha}\ast F(u))f(u), \quad \quad \hbox{in }\mathbb{R ...
Deng, Shengbing, Yu, Junwei
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Multiple normalized solutions for fractional (p,q)-Laplacian equations

open access: yesElectronic Journal of Differential Equations
In this article, we consider the multiplicity results of normalized solutions of the fractional $(p,q)$-Laplacian equation $$\displaylines{ (-\Delta)_p^{s} u+(-\Delta)_q^{s} u=\lambda |u|^{p-2}u+h(\varepsilon x)f(u)+g(u) \quad\text{in }\mathbb{R}^N,\cr ...
Lihong Bao, Libo Wang, Min Li
doaj  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Normalized solutions for the Choquard equations with critical nonlinearities

open access: yesAdvances in Nonlinear Analysis
This study is concerned with the existence of normalized solutions for the Choquard equations with critical nonlinearities −Δu+λu=f(u)+(Iα∗∣u∣2α*)∣u∣2α*−2u,inRN,∫RN∣u∣2dx=a2,\left\{\begin{array}{l}-\Delta u+\lambda u=f\left(u)+\left({I}_{\alpha }\ast ...
Gao Qian, He Xiaoming
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Normalized solutions for the Choquard equation with potential and combined nonlinearities

open access: yesAdvances in Nonlinear Analysis
In this paper, we study multiple normalized solutions for the following Choquard equation:
Xing Wenjun, Suo Hongmin, Lei Chunyu
doaj   +1 more source

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