Results 171 to 180 of about 994,574 (330)

Phase-Function Normalization in the 3-D Discrete-Ordinates Solution of Radiative Transfer—PART II: Benchmark Comparisons

, 2012
Brian Hunter, Zhixiong Guo
openalex   +2 more sources

Normalized Solutions to Schrödinger Equations with Critical Exponent and Mixed Nonlocal Nonlinearities

, 2022
Yanheng Ding, Huayang Wang
openalex   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Existence of solutions to a normalized F-infinity Laplacian equation

Electronic Journal of Differential Equations, 2014
In this article, for a continuous function F that is twice differentiable at a point $x_0$, we define the normalized F-infinity Laplacian $\Delta_{F; \infty}^N$ which is a generalization of the usual normalized infinity Laplacian. Then for a bounded
Hua Wang, Yijun He
doaj  

Normalized solutions for the Choquard equation with mass supercritical nonlinearity

, 2022
Na Xu, Shiwang Ma
openalex   +2 more sources

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Normalized solutions for fractional Schrodinger-Choquard systems with Sobolev critical coupled nonlinearity

Electronic Journal of Differential Equations
We study the existence of normalized solutions for a system of fractional Schrodinger-Choquard with Sobolev critical coupling term. We obtain the existence of the positive normalized ground state solution, and in a special case we obtain a mountain ...
Zilin Chen, Yang Yang
doaj  

Equivalence of viscosity and weak solutions for the normalized $p(x)$-Laplacian

, 2017
Jarkko Siltakoski
openalex   +2 more sources