Results 171 to 180 of about 7,704,118 (361)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Normalized solutions for Sobolev critical Schrodinger-Bopp-Podolsky systems

Electronic Journal of Differential Equations, 2023
Yuxin Li, Xiaojun Chang, Zhaosheng Feng
doaj  

The existence and asymptotic behaviours of normalized solutions for critical fractional Schrödinger equation with Choquard term

, 2022
Meng Li, Jinchun He, Haoyuan Xu, Mei-hua Yang   +3 more
openalex   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

An action approach to nodal and least energy normalized solutions for nonlinear Schrödinger equations [PDF]

arXiv
We develop a new approach to the investigation of normalized solutions for nonlinear Schr\"odinger equations based on the analysis of the masses of ground states of the corresponding action functional. Our first result is a complete characterization of the masses of action ground states, obtained via a Darboux-type property for the derivative of the ...
arxiv  

Non-singular solutions of normalized Ricci flow on noncompact manifolds of finite volume

, 2008
Fuquan Fang, Yuguang Zhang, Zhenlei Zhang   +2 more
openalex   +2 more sources

Existence and multiplicity of normalized solutions for the nonlinear Chern–Simons–Schrödinger equations

, 2020
Haibo Chen, Weihong Xie
openalex   +1 more source

Existence and asymptotic behavior of normalized solutions for the modified Kirchhoff equations in $ \mathbb{R}^3 $

, 2022
Zhongxiang Wang
openalex   +1 more source

Normalized solutions for Kirchhoff type equations with combined nonlinearities: The Sobolev critical case

Discrete and Continuous Dynamical Systems. Series A, 2023
Xiaojing Feng, Haidong Liu, Zhitao Zhang
semanticscholar   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source