Results 51 to 60 of about 8,131,330 (355)
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa+8 more
wiley +1 more source
In this paper, we study the existence of multiple normalized solutions to the following Schrödinger–Poisson system with general nonlinearities: \begin{equation*} \begin{cases} -\varepsilon^2\Delta u+V(x)u+\phi u=f(u)+\lambda u & \hbox{in $\mathbb{R}
Siwei Wei, Kaimin Teng
doaj +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang+2 more
wiley +1 more source
Normalized solution for a kind of coupled Kirchhoff systems
In this paper, we investigate the existence of a normalized solution for the following Kirchhoff system in the entire space $ \mathbb{R}^N $ ($ N\geq3 $): \begin{document}$ \begin{align*} \begin{cases}-\left(1+\int_{ \mathbb{R}^N}|\nabla u|^2dx\right)\
Shiyong Zhang, Qiongfen Zhang
doaj +1 more source
Normalized solutions of Kirchhoff equations with Hartree-type nonlinearity
In the present paper, we prove the existence of the solutions (λ, u) ∈ ℝ × H1(ℝ3) to the following Kirchhoff equations with the Hartree-type nonlinearity under the general mass supercritical settings, {-(a+b∫ℝ3|∇u|2dx)Δu-λu=[Iα*(K(x)F(u))]K(x)f(u),u∈H1 ...
Yuan Shuai, Gao Yuning
doaj +1 more source
Remarks on the spherical waves of the Dirac field on de Sitter spacetime
The Shishkin's solutions of the Dirac equation in spherical moving frames of the de Sitter spacetime are investigated pointing out the set of commuting operators whose eigenvalues determine the integration constants.
Abramowitz M.+5 more
core +1 more source
A Hollerith Technique for the Solution of Normal Equations
IN THlE critical study of the results of large-scale sample surveys it is frequently necessary to consider data classified in several different ways, and to attempt to disentangle the effects of the various classifications which will usually not be orthogonal to one another.
Healy, M. J. R., Dyke, G. V.
openaire +2 more sources
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp+5 more
wiley +1 more source
In this paper we study the following nonlinear fractional Hartree (or Choquard-Pekar) equation (−Δ)su+μu=(Iα*F(u))F′(u) inRN, ${\left(-{\Delta}\right)}^{s}u+\mu u=\left({I}_{\alpha }{\ast}F\left(u\right)\right){F}^{\prime }\left(u\right)\quad \text{in} {\
Cingolani Silvia+2 more
doaj +1 more source