Results 81 to 90 of about 82,544 (332)
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Classical simulations of Abelian-group normalizer circuits with intermediate measurements
Quantum normalizer circuits were recently introduced as generalizations of Clifford circuits [arXiv:1201.4867]: a normalizer circuit over a finite Abelian group $G$ is composed of the quantum Fourier transform (QFT) over G, together with gates which ...
Bermejo-Vega, Juan +1 more
core
The period functions' higher order derivatives [PDF]
We prove a formula for the $n$-th derivative of the period function $T$ in a period annulus of a planar differential system. For $n = 1$, we obtain Freire, Gasull and Guillamon formula for the period's first derivative \cite{FGG}.
Sabatini, Marco
core +2 more sources
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Epimetheus - a multi-profile normalizer for epigenomic sequencing data
Background Exponentially increasing numbers of NGS-based epigenomic datasets in public repositories like GEO constitute an enormous source of information that is invaluable for integrative and comparative studies of gene regulatory mechanisms.
Mohamed-Ashick M. Saleem +4 more
doaj +1 more source
Bayesian filtering unifies adaptive and non-adaptive neural network optimization methods
We formulate the problem of neural network optimization as Bayesian filtering, where the observations are the backpropagated gradients. While neural network optimization has previously been studied using natural gradient methods which are closely related
Aitchison, Laurence
core
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Multiple Approaches of Neuro-Physiotherapy Used for Improving Balance, Normalizing Tone, and Gait Training in a Child With Ataxic Cerebral Palsy: A Case Report [PDF]
Dhanashree Upganlawar +3 more
openalex +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Conjugacy separability of certain HNN extensions with normal associated subgroups [PDF]
In this paper, we will give necessary and sufficient conditions for certain HNNextensions of subgroup separable groups with normal associated subgroup to be conjugacyseparable.
Kok Bin Wong, Peng Choon Wong
doaj

