Results 181 to 190 of about 64,482 (311)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Liquid Biopsy Biomarkers for Cervical Cancer: A Systematic Review. [PDF]

Int J Mol Sci
Pineda-Migranas JA, Bravata-Alcántara JC, Cortés-Ortíz IA, Cortés-Malagón EM, de Los Ángeles Romero-Tlalolini M, Sierra-Martínez M, Acosta-Altamirano G.   +6 more
europepmc   +1 more source

Normalization and Standardization in Deep Learning: An Empirical Benchmarking Towards Optimal Feature Scaling Strategies

Revista, Zen, IA, 10
openalex   +1 more source

Estimating snow cover area in south of Turkey using the Normalized Difference Snow Index (NDSI) form MODIS Satellite Images

, 2019
Adnan Hashim Abdulkadhim
openalex   +1 more source

The normalized Laplacian spectra of the double corona based on $R$-graph [PDF]

, 2017
Ping-Kang Yu, Gui‐Xian Tian
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Seasonality of total coccolith fluxes and Normalized fluxes. (A) Total coccolith fluxes (coccoliths per m^-2 d^-1 x 10⁹; blue bars) and (B) the normalized flux, deviation from the annual mean coccolith flux, with the sample number for the Perdido and Coatzacoalcos traps.

Felipe de Jesús García-Romero (22567239), Juan Carlos Herguera García (22567242), Jörg Bollmann (7134611), José Rubén Lara Lara (22567245), Mara Yadira Cortés Martínez (22567248), Amaru Márquez-Artavia (22567251)   +5 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Reference Gene Stability in <i>Agrostemma githago</i> Using Quantitative Real-Time PCR. [PDF]

Int J Mol Sci
Bielecka M, Pencakowski B, Stafiniak M, Kozłowska W, Dziwak M, Nowis K, Łaczmański Ł, Matkowski A.   +7 more
europepmc   +1 more source

Global 1km Resolution 2000-2024 Annual Maximum Composite Normalized Difference Vegetation Index (NDVI) Dataset

song rui xiang
openalex   +1 more source