Results 41 to 50 of about 1,590 (239)
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
A Note on the First Integrals of Vector Fields with Integrating Factors and Normalizers
We prove a sufficient condition for the existence of explicit first integrals for vector fields which admit an integrating factor. This theorem recovers and extends previous results in the literature on the integrability of vector fields which are volume
Jaume Llibre, Daniel Peralta-Salas
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Groups with the same orders of Sylow normalizers as the Mathieu groups
There exist many characterizations for the sporadic simple groups. In this paper we give two new characterizations for the Mathieu sporadic groups. Let M be a Mathieu group and let p be the greatest prime divisor of |M|. In this paper, we prove that M is
Behrooz Khosravi, Behnam Khosravi
doaj +1 more source
Graph-based Turkish text normalization and its impact on noisy text processing
User generated texts on the web are freely-available and lucrative sources of data for language technology researchers. Unfortunately, these texts are often dominated by informal writing styles and the language used in user generated content poses ...
Seniz Demir, Berkay Topcu
doaj +1 more source
Summary In this article we continue the formalization of field theory in Mizar [1], [2], [4], [3]. We introduce normal extensions: an (algebraic) extension E of F is normal if every polynomial of F that has a root in E already splits in E.
openaire +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Groups with finitely many normalizers of non-subnormal subgroups
It is proved that a group G has finitely many normalizers of non-subnormal subgroups if and only if each subgroup of G either is subnormal or has finitely many conjugates; groups with this latter property have been completely described in [8].
Fausto De Mari, Francesco De Giovanni
doaj
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Reverse-transcription quantitative real-time polymerase chain reaction (RT-qPCR) is the most used, fast, and reproducible method to confirm large-scale gene expression data.
Gilbert O. Silveira +8 more
doaj +1 more source

