Results 61 to 70 of about 64,482 (311)
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Prussian Blue Nanozyme Normalizes Microenvironment to Delay Osteoporosis (Adv. Healthcare Mater. 19/2022) [PDF]
Chenyi Ye +11 more
openalex +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Reverse-transcription quantitative real-time polymerase chain reaction (RT-qPCR) is the most used, fast, and reproducible method to confirm large-scale gene expression data.
Gilbert O. Silveira +8 more
doaj +1 more source
An extension of the Glauberman ZJ-Theorem
Let $p$ be an odd prime and let $J_o(X)$, $J_r(X)$ and $J_e(X)$ denote the three different versions of Thompson subgroups for a $p$-group $X$. In this article, we first prove an extension of Glauberman's replacement theorem.
Kızmaz, Muhammet Yasir
core +2 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
We determine the groups which can appear as the normalizer of a maximal torus in a connected 2-compact group. The technique depends on using ideas of Tits to give a novel description of the normalizer of the torus in a connected compact Lie group, and ...
Andersen +21 more
core +3 more sources
Self-Attentive Spatial Adaptive Normalization for Cross-Modality Domain Adaptation [PDF]
Devavrat Tomar +4 more
openalex +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Selection and testing of reference genes for accurate RT-qPCR in rice seedlings under iron toxicity.
Reverse Transcription quantitative PCR (RT-qPCR) is a technique for gene expression profiling with high sensibility and reproducibility. However, to obtain accurate results, it depends on data normalization by using endogenous reference genes whose ...
Fabiane Igansi de Castro Dos Santos +5 more
doaj +1 more source

