Results 41 to 50 of about 1,575,044 (341)

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Effect of strabismus surgery on torticollis caused by congenital superior oblique palsy in young children

open access: yesIndian Journal of Ophthalmology, 2014
Purpose: To evaluate the outcome of strabismus surgery for congenital superior oblique palsy (SOP) in relation to correction of head tilt and hypertropia. The cohort of patients mainly involved very young children.
Ramesh Kekunnaya, Sherwin J Isenberg
doaj   +1 more source

Normative Practical Reasoning via Argumentation and Dialogue [PDF]

open access: yes, 2016
Postprin
De Vos, Marina   +3 more
core   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Responding to unauthorized residence: on a dilemma between ‘firewalls’ and ‘regularizations’

open access: yesComparative Migration Studies
Residence of unauthorized immigrants is a stable feature of the Global North’s liberal democracies. This article asks how liberal-democratic policymakers should respond to this phenomenon, assuming both that states have incontrovertible rights and ...
Lukas Schmid
doaj   +1 more source

Institutional Policies on Artificial Intelligence in Higher Education: Frameworks and Best Practices for Faculty

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This article explores institutional policies on artificial intelligence (AI) in higher education. As AI tools become increasingly utilized in academia—from research and teaching to assessment and student support—institutions face growing pressure to establish clear, ethical, and practical guidelines to help guide faculty.
Lauren Azevedo   +3 more
wiley   +1 more source

Promoting the application of policy documents by nursing and midwifery staff at the point of care: a mixed-methods study.

open access: yesInternational Journal of Integrated Care, 2019
Introduction: Policy application is essential for normative integration, as the point of care represents the practical meeting point of healthcare priorities common to organisations, professional groups and individuals.
John Newans   +2 more
doaj   +1 more source

Why Metacognition Is Not Always Helpful

open access: yesFrontiers in Psychology, 2020
In many situations, actively engaging in metacognition may improve cognitive achievement and subjective well-being. However, the potential disadvantages of metacognitive engagement are only rarely communicated in metacognition research.
Elisabeth Norman, Elisabeth Norman
doaj   +1 more source

The Alienation Objection to Consequentialism [PDF]

open access: yes, 2020
An ethical theory is alienating if accepting the theory inhibits the agent from fitting participation in some normative ideal, such as some ideal of integrity, friendship, or community.
Baker, Calvin, Maguire, Barry
core  

A Review of Norms and Normative Multiagent Systems [PDF]

open access: yesThe Scientific World Journal, 2014
Norms and normative multiagent systems have become the subjects of interest for many researchers. Such interest is caused by the need for agents to exploit the norms in enhancing their performance in a community. The term norm is used to characterize the behaviours of community members.
Moamin A. Mahmoud   +3 more
openaire   +3 more sources

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