Results 71 to 80 of about 1,984,133 (390)

Political Thought as Interdisciplinary Knowledge: A Paradigmatic-Implicative Narration [PDF]

open access: yesInterdisciplinary Studies in the Humanities, 2015
Political thought is the kind of thinking which is formulated in different disciplines; political philosophy, political ideology, political theology, and political literature are some of its important examples. Although in the course of history political
A. Manoochehri
doaj   +1 more source

Essentially Grounded Non-Naturalism and Normative Supervenience [PDF]

open access: yes, 2018
Non-naturalism – roughly the view that normative properties and facts are sui generis and incompatible with a purely scientific worldview – faces a difficult challenge with regard to explaining why it is that the normative features of things supervene on
Teemu, Toppinen
core  

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini   +7 more
wiley   +1 more source

Reasons: Wrong, Right, Normative, Fundamental [PDF]

open access: yes, 2019
Reasons fundamentalists maintain that we can analyze all derivative normative properties in terms of normative reasons. These theorists famously encounter the Wrong Kind of Reasons problem, since not all reasons for reactions seem relevant for reasons ...
Lord, Errol, Sylvan, Kurt
core  

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez   +12 more
wiley   +1 more source

Willing and Able: A General Model of Organizational Responses to Normative Pressures

open access: yesAcademy of Management Review, 2017
We develop a conceptual understanding of when and how organizations respond to normative pressures. More precisely, we examine two main factors underlying the willingness and ability of organizations to respond to an issue: (1) issue salience, and (2 ...
Rodolphe Durand, Olga Hawn, I. Ioannou
semanticscholar   +1 more source

Norms and normativity

open access: yesCalenda, 2017
Collective life is structured by norms. Even though such norms manifest as regularities for those who observe them, they also constitute rules to follow or ideals to mimic. May these norms be social, moral, or legal, they organize practices and orient judgments, especially in the economic sphere.
openaire   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin   +2 more
wiley   +1 more source

Social norms and human normative psychology [PDF]

open access: yes, 2018
Our primary aim in this paper is to sketch a cognitive evolutionary approach for developing explanations of social change that is anchored on the psychological mechanisms underlying normative cognition and the transmission of social norms.
Davis, Taylor, Kelly, Daniel
core  

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer   +14 more
wiley   +1 more source

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