Plasma-Free Metanephrine and Normetanephrine Quantification for Clinical Applications Validated by Combining Solid-Phase Extraction and HPLC-MS/MS [PDF]
MoleculesPlasma-free metanephrines are the most sensitive and specific biochemical markers for diagnosing catecholamine-secreting tumors, such as pheochromocytoma and paraganglioma.
Hyebin Choi +8 more
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Urine-normetanephrine, a predictor of mortality risk in patients with adrenal adenomas [PDF]
Scientific ReportsUrine-metanephrines are used in the screening for pheochromocytomas in patients with adrenal incidentalomas, but their potential as markers for mortality in patients with adrenal adenomas has not been studied. A retrospective cohort study was designed to
Albin Kjellbom +4 more
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Metanephrine and Normetanephrine Urine Excretion in Patients with PCOS [PDF]
Acta Medica Bulgarica, 2022 Aims: The present study aims to investigate the association between catecholamine metabolites (normetanephrine [NMN] and metanephrine [MN]) and polycystic ovarian syndrome (PCOS) and its clinical manifestations.
Robeva R. +4 more
doaj +2 more sources
Pheochromocytoma – clinical manifestations, diagnosis and current perioperative management [PDF]
Journal of Mind and Medical Sciences, 2019 Pheochromocytoma is a neuroendocrine tumor characterized by the excessive production of catecholamines (epinephrine, norepinephrine, and dopamine). The diagnosis is suspected due to hypertensive paroxysms, associated with vegetative phenomena, due to the
Dragos Radu Marcu +5 more
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A hyperadrenergic state in hypertension is associated with depressive symptoms and impaired stress-modulated vasomotor responses: evidence for chronic stress as a common aetiology for a hypertension/depression phenotype [PDF]
BJPsych OpenBackground Noradrenergic activation in the central and peripheral nervous systems is a putative mechanism explaining the link between hypertension and affective disorders.
Bushra Farukh +5 more
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پیاورد سلامت, 2021 Background and Aim: Inactivity increases the risk of chronic diseases. The aim of the present study was to investigate the acute changes in Normetanephrine and glucose in boxing with Kinect Xbox with and without blood flow restriction as an alternative ...
Zeinab Sadat Mousavi +4 more
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Metanephrine and normetanephrine associated with subclinical myocardial injuries in pheochromocytoma and paraganglioma [PDF]
Frontiers in Oncology, 2022 ObjectiveTo analyze the correlation between metanephrine and normetanephrines (MNs) and subclinical myocardial injuries (SMI) diagnosed by low left ventricular global longitudinal strain (LV GLS) in patients with pheochromocytoma and paraganglioma (PPGL).
Yang Yu +10 more
doaj +2 more sources
Construction and validation of a multimodal predictive model incorporating catecholamines and uric acid for early detection of hypertensive organ damage [PDF]
Frontiers in EndocrinologyObjectiveTo investigate the feasibility and clinical value of constructing a predictive model for early detection of organ damage in hypertensive patients based on catecholamine-related indicators (norepinephrine, normetanephrine, and metanephrine ...
Menglin Wang, Haiying Zhao, Dongyu Li
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Pakistan Armed Forces Medical Journal, 2023 Objective: To validate urinary Vanillylmandelic acid (VMA) for screening adrenal medullary disorders, taking plasma-free Metanephrine as the gold standard. Study Design: Cross-sectional validation study.
Usama Bin Khalid +5 more
doaj +3 more sources
Indian Journal of Endocrinology and Metabolism, 2015 Background: Pheochromocytomas (PHEO) and paragangliomas (PGL) are derived from paraganglia of the sympathetic and parasympathetic nervous system. Most of the sympathetic PHEO/PGL secrete either catecholamine or their metabolites, metanephrines, whereas ...
Poonam Gupta +6 more
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