Sulfasalazine-Induced Urinary Normetanephrine Elevation Mimicking Recurrent Phaeochromocytoma—A Case Report [PDF]
Case Reports in EndocrinologyPhaeochromocytomas and paragangliomas (PPGLs) are catecholamine-secreting neuroendocrine tumours (NETs) of the adrenal medulla and autonomic nervous system. Early recognition and management is critical given their potential morbidity and mortality.
Maria Hadjicosti +5 more
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Plasma-Free Metanephrine and Normetanephrine Quantification for Clinical Applications Validated by Combining Solid-Phase Extraction and HPLC-MS/MS [PDF]
MoleculesPlasma-free metanephrines are the most sensitive and specific biochemical markers for diagnosing catecholamine-secreting tumors, such as pheochromocytoma and paraganglioma.
Hyebin Choi +8 more
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A hyperadrenergic state in hypertension is associated with depressive symptoms and impaired stress-modulated vasomotor responses: evidence for chronic stress as a common aetiology for a hypertension/depression phenotype [PDF]
BJPsych OpenBackground Noradrenergic activation in the central and peripheral nervous systems is a putative mechanism explaining the link between hypertension and affective disorders.
Bushra Farukh +5 more
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Presence of Metanephrine and Normetanephrine in Normal Human Urine [PDF]
Nature, 1960 IN 1957, Axelrod reported that epinephrine and norepinephrine were O-methylated at the C-3 position, giving metanephrine (3-O-methylepinephrine) and normetanephrine (3-O-methylnorepinephrine), respectively, in the rat1 ; in addition, he found that these compounds were normally excreted in rat urine2.
E H, LABROSSE, J D, MANN
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Construction and validation of a multimodal predictive model incorporating catecholamines and uric acid for early detection of hypertensive organ damage [PDF]
Frontiers in EndocrinologyObjectiveTo investigate the feasibility and clinical value of constructing a predictive model for early detection of organ damage in hypertensive patients based on catecholamine-related indicators (norepinephrine, normetanephrine, and metanephrine ...
Menglin Wang, Haiying Zhao, Dongyu Li
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Urine-normetanephrine, a predictor of mortality risk in patients with adrenal adenomas [PDF]
Scientific ReportsUrine-metanephrines are used in the screening for pheochromocytomas in patients with adrenal incidentalomas, but their potential as markers for mortality in patients with adrenal adenomas has not been studied. A retrospective cohort study was designed to
Albin Kjellbom +4 more
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Biochemically ‘active’ pheochromocytoma can be clinically ‘silent’ [PDF]
Endocrinology, Diabetes & Metabolism Case ReportsA 55-year-old woman presented with ill-defined right abdominal pain and, on evaluation, was diagnosed to have a large right adrenal mass (9.5×8.5×8.7 cm).
Shinjan Patra +3 more
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Bladder paraganglioma presenting with atypical abdominal pain: A diagnostic challenge [PDF]
Urology Case ReportsA 70-year-old man presented with a 10-day history of intermittent abdominal pain. Initial evaluation revealed a bladder nodule on imaging, but cystoscopy showed no tumor. Subsequent investigations including elevated urinary normetanephrine levels and MRI
Yuchun Luo, Juncheng Huang, Hongwei Liu
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Chromogranin A in diagnosis of pheochromocytoma (comparative analysis) [PDF]
Терапевтический архив, 2021 Aim. To study the prognostic value of determining Chromogranin A blood level in the diagnosis of PHEO. Materials and methods. We conducted a comparative analytical study of 157 patients with suspected PHEO, statistical analysis of 24-hour urinary ...
Marina Yu. Yukina +4 more
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Urinary Free Metanephrines for Diagnosis of Pheochromocytoma and Paraganglioma [PDF]
Endocrinology and Metabolism, 2021 Background Pheochromocytoma and paraganglioma (PPGL) is diagnosed through biochemical confirmation of excessive catecholamines in urine and plasma. Recent technological developments have allowed us to measure urinary free metanephrines; however, the ...
Jiyeon Ahn +6 more
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