Results 51 to 60 of about 2,022 (192)

Giant parathyroid adenoma presenting with multiple pathologic fractures: A case report

Clinical Case Reports, Volume 11, Issue 6, June 2023., 2023
Key Clinical Message Hyperparathyroidism is a common endocrine disorder, which must be suspected in patients presenting with fatigue, history of pathologic fracture and the diagnosis can be confirmed by elevated calcium and PTH levels, and the preferred treatment option.
Hassan Abshirini, Mahsa Heidari, Ali Fahimi, Parastoo Ghorbani, Erfan Ghadirzadeh, Sasan Shafiei   +5 more
wiley   +1 more source

Normocalcaemic hyperparathyroidism (NPHPT) and primary hyperparathyroidism (PHPT): Least significant change (LSC) for adjusted serum calcium [PDF]

, 2021
Introduction: The least significant change (LSC) is a term used in individuals in order to evaluate whether one measurement has changed significantly from the previous one. It is widely used when assessing bone mineral density (BMD) scans. To the best of
Eastell, R., Jacques, R., Oakes, E., Peel, N., Schini, M., Walsh, J.S.   +5 more
core   +1 more source

Ionized hypercalcemia in 238 cats from a referral hospital population (2009‐2019)

Journal of Veterinary Internal Medicine, Volume 37, Issue 1, Page 80-91, January/February 2023., 2023
Abstract Background Ionized calcium concentration ([iCa]) is more sensitive for detecting calcium disturbances than serum total calcium concentration but literature on ionized hypercalcemia in cats is limited. Urolithiasis is a possible adverse consequence of hypercalcemia. Hypothesis/Objectives To describe clinical details of diagnoses associated with
Sophie E. Broughton, Dan G. O'Neill, Harriet M. Syme, Rebecca F. Geddes   +3 more
wiley   +1 more source

Update on Preoperative Parathyroid Localization in Primary Hyperparathyroidism [PDF]

Endocrinology and Metabolism, 2022
Parathyroidectomy is the treatment of choice for primary hyperparathyroidism when the clinical criteria are met. Although bilateral neck exploration is traditionally the standard method for surgery, minimally invasive parathyroidectomy (MIP), or focused ...
Hye-Sun Park, Namki Hong, Jong Ju Jeong, Mijin Yun, Yumie Rhee   +4 more
doaj   +1 more source

Vitamin D Deficiency and the Presentation of Primary Hyperparathyroidism: A Mini Review

International Journal of Endocrinology, Volume 2023, Issue 1, 2023., 2023
The clinical presentation of primary hyperparathyroidism (PHPT) has evolved over the years from a symptomatic disorder to a predominantly asymptomatic condition. Altered vitamin D metabolism seems to play a role in the presentation of PHPT and may exacerbate the severity of disease.
Niharika Yedla, Hyon Kim, Anupa Sharma, Xiangbing Wang, Jaya   +4 more
wiley   +1 more source

Hypopituitarism due to a Large Osteoclastoma Arising from the Sphenoid Bone Invading the Pituitary Fossa in a Patient with Parathyroid Carcinoma

Case Reports in Endocrinology, Volume 2023, Issue 1, 2023., 2023
Background. Parathyroid carcinoma accounts for <1% of cases of primary hyperparathyroidism (PHPT). This rare condition may present with severe hypercalcemia and bone complications such as osteoclastomas and pathologic fractures. Here, we present a rare condition of panhypopituitarism resulting from an osteoclastoma in the sphenoid bone that invaded the
Leonardo Bandeira, Lucian Batista de Oliveira, Maria Vitória Silva de Lima, Daniella Rêgo, Luiz Griz, Francisco Bandeira, Toshihiro Kita   +6 more
wiley   +1 more source

Diagnóstico e manejo do hiperparatireoidismo primário: uma posição científica do Departamento de Metabolismo Ósseo, a Sociedade Brasileira de Endocrinologia e Metabolismo [PDF]

, 2013
OBJECTIVE: To conduct a literature review on the diagnosis and management of primary hyperparathyroidism including the classical hipercalcemic form as well as the normocalcemic variant.
Bandeira, Francisco, Bilezikian, John, Borba, Victoria Zeghbi Cochenski, Borges, João Lindolfo, Borges, Lívia Maria, Carvalho, Nara Crispim, Castro, Luiz Cláudio de, Chaves, Narriane, Griz, Luiz, Lazaretti-Castro, Marise   +9 more
core   +3 more sources

Recent advances in the understanding and management of primary hyperparathyroidism [version 1; peer review: 2 approved]

F1000Research, 2020
Primary hyperparathyroidism is a hormonal disorder whose prevalence is approximately 1–2% in the United States of America. The disease has become more recognizable to clinicians in an earlier phase and, at present, patients can be diagnosed with “classic”
Melanie Goldfarb, Frederick R. Singer
doaj   +1 more source

Epidemiology, Pathophysiology, and Genetics of Primary Hyperparathyroidism

Journal of Bone and Mineral Research, Volume 37, Issue 11, Page 2315-2329, November 2022., 2022
The prevalence and incidence of PHPT vary around the world and depend on a number of factors, the most important being availability of serum calcium (and parathyroid hormone) measurement for screening, which in the Western world has shifted its presentation to an asymptomatic disorder.
Salvatore Minisola, Andrew Arnold, Zhanna Belaya, Maria Luisa Brandi, Bart L. Clarke, Fadil M. Hannan, Lorenz C. Hofbauer, Karl L. Insogna, André Lacroix, Uri Liberman, Andrea Palermo, Jessica Pepe, René Rizzoli, Robert Wermers, Rajesh V. Thakker   +14 more
wiley   +1 more source

Normocalcaemic hypoparathyroidism: prevalence and effect on bone status in older women. The OPUS study. [PDF]

, 2015
There are no consistent data on the prevalence and bone status of normocalcaemic hypoparathyroidism (NHYPO) as defined by normal adjusted calcium and low PTH level.
Bilezikian, Costa, Cusano, Cusano, Cusano, Eastell, Frazao, Glüer, Hannan, Hannan, Hunter, James, Kapur, Kemp, Khosla, Kifor, Levey, Looker, Lowe, Lundgren, Minisola, Monchik, O'neill, Okabe, Oltmann, Pallais, Pallais, Riggs, Rubin, Schussheim, Shibli-Rahhal, Sikjaer, Silverberg, Tordjman, Udelsman, Winer   +35 more
core   +1 more source