Erythrocyte tropism of malarial parasites: The reticulocyte appeal [PDF]
Frontiers in Microbiology, 2022 Erythrocytes are formed from the enucleation of erythroblasts in the bone marrow, and as erythrocytes develop from immature reticulocytes into mature normocytes, they undergo extensive cellular changes through their passage in the blood. During the blood
Bruce Russell +2 more
exaly +4 more sources
Rodent Malaria Erythrocyte Preference Assessment by an Ex Vivo Tropism Assay [PDF]
Frontiers in Cellular and Infection Microbiology, 2021 Circulating red blood cells consist of young erythrocytes (early and late reticulocytes) and mature erythrocytes (normocytes). The human malaria parasites, Plasmodium falciparum and P.
Laurent Renia +2 more
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Experimental malaria-associated acute respiratory distress syndrome is dependent on the parasite-host combination and coincides with normocyte invasion [PDF]
Malaria Journal, 2018 Background Malaria-associated acute respiratory distress syndrome (MA-ARDS) is a complication of malaria with a lethality rate of up to 80% despite anti-malarial treatment.
Leen Vandermosten +2 more
exaly +4 more sources
Sequential roles for red blood cell binding proteins enable phased commitment to invasion for malaria parasites [PDF]
Nature Communications, 2023 Invasion of red blood cells (RBCs) by Plasmodium merozoites is critical to their continued survival within the host. Two major protein families, the Duffy binding-like proteins (DBPs/EBAs) and the reticulocyte binding like proteins (RBLs/RHs) have been ...
Melissa N. Hart +8 more
doaj +2 more sources
The Consequences of Mixed-Species Malaria Parasite Co-Infections in Mice and Mosquitoes for Disease Severity, Parasite Fitness, and Transmission Success [PDF]
Frontiers in Immunology, 2020 The distributions of human malaria parasite species overlap in most malarious regions of the world, and co-infections involving two or more malaria parasite species are common. Little is known about the consequences of interactions between species during
Jianxia Tang +4 more
doaj +2 more sources
The Unexpected Diagnosis of Hepatic Tuberculosis in an Immunocompetent Patient. [PDF]
Case Rep Surg, 2020 Background/Aim. Tuberculosis (TB) is a chronic infectious disease which affects millions. The most affected system is the respiratory. Thus, hepatic TB (HTB) without involvement of other organs is not common. Its clinical manifestations are not specific, and both imaging and histopathological findings are necessary for the diagnosis.
Garmpis N +4 more
europepmc +2 more sources
Plasmodium vivax Reticulocyte Binding Proteins for invasion into reticulocytes. [PDF]
Cell Microbiol, 2020 Abstract Plasmodium vivax is responsible for most of the malaria infections outside Africa and is currently the predominant malaria parasite in countries under elimination programs. P. vivax preferentially enters young red cells called reticulocytes. Advances in understanding the molecular and cellular mechanisms of entry are hampered by the inability ...
Chan LJ +3 more
europepmc +2 more sources
Plasmodium knowlesi genome sequences from clinical isolates reveal extensive genomic dimorphism. [PDF]
PLoS ONE, 2015 Plasmodium knowlesi is a newly described zoonosis that causes malaria in the human population that can be severe and fatal. The study of P. knowlesi parasites from human clinical isolates is relatively new and, in order to obtain maximum information from
Miguel M Pinheiro +8 more
doaj +2 more sources
Clustering and genetic differentiation of the normocyte binding protein (nbpxa) of Plasmodium knowlesi clinical isolates from Peninsular Malaysia and Malaysia Borneo [PDF]
Malaria Journal, 2016 Md Atique Ahmed +2 more
exaly +2 more sources
An algorithm to detect overlapping red blood cells for sickle cell disease diagnosis
IET Image Processing, Volume 16, Issue 6, Page 1669-1677, May 2022., 2022 Abstract In Africa, Uganda is among the countries with a high number of babies (20,000 babies) born with sickle cell, contributing between 6.8% of the children born with sickle cell every year worldwide and approximately 4.5% of the children born with hemoglobinopathies worldwide.
Mabirizi Vicent +2 more
wiley +1 more source