Results 21 to 30 of about 259 (133)

Anti-malarial activity of geldanamycin derivatives in mice infected with Plasmodium yoelii

Malaria Journal, 2012
Background Geldanamycin (GA), a benzoquinone ansamycin antibiotic has been shown in vitro to possess anti-plasmodial activity. Pharmacological activity of this drug is attributed to its ability to inhibit PfHSP90.
Mout Rubul, Xu Zhi-Dong, Wolf Angela K H, Jo Davisson Vincent, Jarori Gotam K   +4 more
doaj   +1 more source

The Influence of Oxidative Stress and Natural Antioxidants on Morphometric Parameters of Red Blood Cells, the Hemoglobin Oxygen Binding Capacity, and the Activity of Antioxidant Enzymes

BioMed Research International, Volume 2019, Issue 1, 2019., 2019
Using a wide range of different physical and chemical methods, it was found that the oxidative stress caused by addition of hydrogen peroxide to the incubation medium has a significant effect on the conformation of haematoporphyrin, influencing the oxygen‐binding properties of haemoglobin in red blood cells.
Victor V. Revin, Natalia V. Gromova, Elvira S. Revina, Anastasia Yu. Samonova, Alexander Yu. Tychkov, Svetlana S. Bochkareva, Alexander A. Moskovkin, Tatyana P. Kuzmenko, Kazim Husain   +8 more
wiley   +1 more source

Two functional reticulocyte binding-like (RBL) invasion ligands of zoonotic Plasmodium knowlesi exhibit differential adhesion to monkey and human erythrocytes

Malaria Journal, 2012
Background Plasmodium knowlesi is a monkey malaria species that is becoming a serious public health concern infecting hundreds and perhaps thousands of humans in Southeast Asia.
Semenya Amma A, Tran Tuan M, Meyer Esmeralda VS, Barnwell John W, Galinski Mary R   +4 more
doaj   +1 more source

Helminth Parasites Alter Protection against Plasmodium Infection

BioMed Research International, Volume 2014, Issue 1, 2014., 2014
More than one‐third of the world’s population is infected with one or more helminthic parasites. Helminth infections are prevalent throughout tropical and subtropical regions where malaria pathogens are transmitted. Malaria is the most widespread and deadliest parasitic disease.
Víctor H. Salazar-Castañon, Martha Legorreta-Herrera, Miriam Rodriguez-Sosa, Abraham Landa-Piedra   +3 more
wiley   +1 more source

Extracellular vesicles in parasitic diseases

Journal of Extracellular Vesicles, Volume 3, Issue 1, January 2014., 2014
Parasitic diseases affect billions of people and are considered a major public health issue. Close to 400 species are estimated to parasitize humans, of which around 90 are responsible for great clinical burden and mortality rates. Unfortunately, they are largely neglected as they are mainly endemic to poor regions.
Antonio Marcilla, Lorena Martin‐Jaular, Maria Trelis, Armando de Menezes‐Neto, Antonio Osuna, Dolores Bernal, Carmen Fernandez‐Becerra, Igor C. Almeida, Hernando A. del Portillo   +8 more
wiley   +1 more source

Morphological Features of Red Blood Cells in Patients with Severe Concomitant Injury

Общая реаниматология, 2013
Objective: to reveal changes in the structure and shape of red blood cells depending on blood loss (BL) volume in patients with severe concomitant injury (SCI). Subjects and methods.
V. V. Moroz, E. A. Myagkova, V. A. Sergunova, O. E., Gudkova, D. A. Ostapchenko, A. M Chernysh, V. I. Reshetnyak   +6 more
doaj   +1 more source

Plasticity in transmission strategies of the malaria parasite, Plasmodium chabaudi: environmental and genetic effects

Evolutionary Applications, Volume 6, Issue 2, Page 365-376, February 2013., 2013
Abstract Parasites may alter their behaviour to cope with changes in the within‐host environment. In particular, investment in transmission may alter in response to the availability of parasite resources or host immune responses. However, experimental and theoretical studies have drawn conflicting conclusions regarding parasites' optimal (adaptive ...
Angus Cameron, Sarah E. Reece, Damien R. Drew, Daniel T. Haydon, Andrew J. Yates   +4 more
wiley   +1 more source

Pathological Changes in the Liver Parenchyma of Reptiles as a Factor Influencing the Processes of Hematopoiesis (on the Example of Lacertidae: Eremias arguta)

Zoodiversity
The influence of liver repair processes on haematopoiesis in scaly reptiles, in particular the steppe runner Eremias arguta (Pallas, 1773) is considered.
N. M. Akulenko
doaj   +1 more source

Safety and Immunogenicity of Recombinant Adeno‐Associated Virus‐Vectored African Swine Fever Virus Antigens

Veterinary Medicine International, Volume 2025, Issue 1, 2025.
Despite the significant global economic damage caused by African swine fever (ASF) and ongoing developments in the field of specific prevention tools development, safe and effective vaccines are still missing. A critical factor hindering the development of ASF vaccines is the lack of sufficient data on the pathogenesis of the virus, as well as a deep ...
Antonina Galeeva, Marina Efimova, Gennadiy Frolov, Nail Khammadov, Almaz Hisamutdinov, Lenar Garipov, Danil Mingaleev, Rustam Ravilov, Sumanta Nandi   +8 more
wiley   +1 more source

A strange case of normocytic anemia

Health, 2010
This case-report underlines the difficulties of a correct diagnosis in a complex vitamin malnutrition that is seldom suspected in patients living in developed Countries with a good social and economic situation. A 79-year-old woman was admitted to hospital with progressive fatigue, dyspnea till orthopnea, pallor and lumbar pain. On physical examination
Morolli, Luca, Montomoli, Jonathan, Lazzarini, Davide, Ioli, Giorgio   +3 more
openaire   +3 more sources