Results 21 to 30 of about 159 (114)

The Unexpected Diagnosis of Hepatic Tuberculosis in an Immunocompetent Patient

Case Reports in Surgery, Volume 2020, Issue 1, 2020., 2020
Background/Aim. Tuberculosis (TB) is a chronic infectious disease which affects millions. The most affected system is the respiratory. Thus, hepatic TB (HTB) without involvement of other organs is not common. Its clinical manifestations are not specific, and both imaging and histopathological findings are necessary for the diagnosis.
Nikolaos Garmpis, Christos Damaskos, Anna Garmpi, Aliki Liakea, Dimitrios Mantas, Muthukumaran Rangarajan   +5 more
wiley   +1 more source

Anti-malarial activity of geldanamycin derivatives in mice infected with Plasmodium yoelii

Malaria Journal, 2012
Background Geldanamycin (GA), a benzoquinone ansamycin antibiotic has been shown in vitro to possess anti-plasmodial activity. Pharmacological activity of this drug is attributed to its ability to inhibit PfHSP90.
Mout Rubul, Xu Zhi-Dong, Wolf Angela K H, Jo Davisson Vincent, Jarori Gotam K   +4 more
doaj   +1 more source

The Consequences of Mixed-Species Malaria Parasite Co-Infections in Mice and Mosquitoes for Disease Severity, Parasite Fitness, and Transmission Success

Frontiers in Immunology, 2020
The distributions of human malaria parasite species overlap in most malarious regions of the world, and co-infections involving two or more malaria parasite species are common. Little is known about the consequences of interactions between species during
Jianxia Tang, Jianxia Tang, Thomas J. Templeton, Jun Cao, Richard Culleton   +4 more
doaj   +1 more source

Gene knock-in as a tool to phenotype clinically relevant varient alleles for studies on malaria pathobiology: proof of concept using the plasmodium knowlesi normocyte binding protein Xa gene [PDF]

, 2018
The zoonotic parasite, Plasmodium knowlesi, is one of five human malaria species. P. knowlesi is geographically restricted to locations of the long-tailed and pig-tailed macaque, indigenous across South-East Asia (SEA). Initial research showed that P.
Millar, Scott B.
core   +2 more sources

Two functional reticulocyte binding-like (RBL) invasion ligands of zoonotic Plasmodium knowlesi exhibit differential adhesion to monkey and human erythrocytes

Malaria Journal, 2012
Background Plasmodium knowlesi is a monkey malaria species that is becoming a serious public health concern infecting hundreds and perhaps thousands of humans in Southeast Asia.
Semenya Amma A, Tran Tuan M, Meyer Esmeralda VS, Barnwell John W, Galinski Mary R   +4 more
doaj   +1 more source

The Influence of Oxidative Stress and Natural Antioxidants on Morphometric Parameters of Red Blood Cells, the Hemoglobin Oxygen Binding Capacity, and the Activity of Antioxidant Enzymes

BioMed Research International, Volume 2019, Issue 1, 2019., 2019
Using a wide range of different physical and chemical methods, it was found that the oxidative stress caused by addition of hydrogen peroxide to the incubation medium has a significant effect on the conformation of haematoporphyrin, influencing the oxygen‐binding properties of haemoglobin in red blood cells.
Victor V. Revin, Natalia V. Gromova, Elvira S. Revina, Anastasia Yu. Samonova, Alexander Yu. Tychkov, Svetlana S. Bochkareva, Alexander A. Moskovkin, Tatyana P. Kuzmenko, Kazim Husain   +8 more
wiley   +1 more source

Helminth Parasites Alter Protection against Plasmodium Infection

BioMed Research International, Volume 2014, Issue 1, 2014., 2014
More than one‐third of the world’s population is infected with one or more helminthic parasites. Helminth infections are prevalent throughout tropical and subtropical regions where malaria pathogens are transmitted. Malaria is the most widespread and deadliest parasitic disease.
Víctor H. Salazar-Castañon, Martha Legorreta-Herrera, Miriam Rodriguez-Sosa, Abraham Landa-Piedra   +3 more
wiley   +1 more source

Extracellular vesicles in parasitic diseases

Journal of Extracellular Vesicles, Volume 3, Issue 1, January 2014., 2014
Parasitic diseases affect billions of people and are considered a major public health issue. Close to 400 species are estimated to parasitize humans, of which around 90 are responsible for great clinical burden and mortality rates. Unfortunately, they are largely neglected as they are mainly endemic to poor regions.
Antonio Marcilla, Lorena Martin‐Jaular, Maria Trelis, Armando de Menezes‐Neto, Antonio Osuna, Dolores Bernal, Carmen Fernandez‐Becerra, Igor C. Almeida, Hernando A. del Portillo   +8 more
wiley   +1 more source

Plasticity in transmission strategies of the malaria parasite, Plasmodium chabaudi: environmental and genetic effects

Evolutionary Applications, Volume 6, Issue 2, Page 365-376, February 2013., 2013
Abstract Parasites may alter their behaviour to cope with changes in the within‐host environment. In particular, investment in transmission may alter in response to the availability of parasite resources or host immune responses. However, experimental and theoretical studies have drawn conflicting conclusions regarding parasites' optimal (adaptive ...
Angus Cameron, Sarah E. Reece, Damien R. Drew, Daniel T. Haydon, Andrew J. Yates   +4 more
wiley   +1 more source

A screen shot of Artemis DNA view comparing six Plasmodium knowlesi genome sequences from patient isolates to the Plasmodium knowlesi H strain reference genome sequence.

, 2015
The P. knowlesi normocyte binding protein xa locus on chromosome 14 is shown. The screen shot shows segregation of the sequences from patient isolates into two groups, (n = 3 in each group) and the dimorphism is clearly visible.
Miguel M. Pinheiro (615585), Thomas D. Otto (188722), Md Atique Ahmed (716047), Theo Sanderson (5662720), Janet Cox-Singh (218129), Julian C. Rayner (121198), Scott B. Millar (615592), Woon Chan Lu (716048), Sanjeev Krishna (4917)   +8 more
core   +1 more source