Results 111 to 120 of about 890,913 (263)
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
THE RELEVANCE OF MACNEIL'S RELATIONAL NORMS TO UNDERSTAND THE EXIT OF A INTERORGANIZATIONAL RELATIONSHIP [PDF]
Relationship marketing has been gaining an increasing interest in the marketing community for the past ten years. Some authors define relationship building and management as the core of the marketing process (Grönroos, 1994), others view it as a way to ...
Isabelle Prim-Allaz, Jean Perrien
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Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Homo Socionicus: a Case Study of Simulation Models of Norms [PDF]
This paper describes a survey of normative agent-based social simulation models. These models are examined from the perspective of the foundations of social theory. Agent-based modelling contributes to the research program of methodological individualism.
Martin Neumann
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This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
An Experimental Study of Conventions and Norms [PDF]
Although it is now recognized that norms play an important role in many economic decisions, compliance with conventions is generally considered to be driven by rational self-interest only.
Luigi Mittone, Francesco Guala
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The effects of a social norms marketing message on self-reported drinking behaviors of college students [PDF]
Plan BThis pilot study investigated the immediate effects of providing college students with social norms messages regarding peer alcohol consumption on a self-report measure of drinking behaviors.
Siders, Jennifer J.
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NPE - A Conceptual Model and Language for the Representation of Norms
Originating in Deontic logic, norms and normative facts enable philosophers, designers and developers to reason over actions an actor may or may not perform with respect to social rules.
Walters, Robert +2 more
core +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Social capital, social norms and the New Institutional Economics [PDF]
Douglass North (1990) describes institutions as the rules of the game that set limits on human behavior, now a universally-accepted definition. North and others especially underline the crucial role of informal social norms.
Keefer, Philip, Knack, Stephen
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