Results 131 to 140 of about 1,696,544 (312)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
The Sociology of Law potential: exploring its scientific landscape
Frontiers in Sociology, 2023 Håkan Hydén, Håkan Hydén
doaj +1 more source
, 2011 The workshop is sponsored by: The Belfer Center for Science and International Affairs at the Harvard Kennedy School of Government. The Canada Centre for Global Security Studies and Citizen Lab at the University of Toronto’s Munk School of Global ...
Hurwitz, Roger, Nye, Joseph
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Social Norms as a Barrier to Women’s Employment in Developing Countries
IMF Economic Review, 2020 S. Jayachandran
semanticscholar +1 more source
A Multi-Method Approach to Identifying Norms and Normative Expectations within a Corporate Hierarchy: Evidence from the Financial Services Industry [PDF]
This paper presents the results of a field study at a large financial services firm that combines multiple methods, including two economic experiments, to measure ethical norms and their behavioral correlates.
Burks, Stephen V., Krupka, Erin L.
core
Enforcement of Contribution Norms in Public Good Games with Heterogeneous Populations [PDF]
Economic and social interaction takes place between individuals with heterogeneous characteristics. We investigate experimentally the emergence and informal enforcement of different contribution norms to a public good in homogeneous and different ...
Riedl, Arno, Reuben, Ernesto
core +2 more sources
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Integrity Building and Social Norms in Kosovo’s Municipalities
, 2018 Why do 'integrity building' interventions in development settings rarely induce governance practices that are consistent with the standards set out in the formal state?
Jackson, David
core
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source