Results 71 to 80 of about 2,302,141 (295)
Distorsions et dilemmes du système performatif de l’aide internationale au développement
Revue Internationale des Études du Développement, 2020 Between the increasing ambitions attributed to international aid and the limited resources to achieve them, the normative and performative injunctions repeated by financial backers and international organizations have never been so strong.
Anne Le Naëlou +2 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Estimating Norms of Commutators
, 2013 We find estimates on the norms commutators of the form [f(x), y] in terms of the norm of [x, y] assuming that x and y are contractions in a C*-algebra A, with x normal and with spectrum within the domain of f.
Loring, Terry A., Vides, Fredy
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Apprendre à enseigner à l’école primaire. Une socialisation professionnelle paradoxale ?
Cahiers de la Recherche sur l'Education et les Savoirs, 2018 At the end of a long research integrating the contributions of many works, we analyze here the recurring evolution of the priorities for new teachers in primary school.
Stéphan Mierzejewski +3 more
doaj +1 more source
Estimating operator norms using covering nets [PDF]
, 2015 We present several polynomial- and quasipolynomial-time approximation schemes for a large class of generalized operator norms. Special cases include the $2\rightarrow q$ norm of matrices for $q>2$, the support function of the set of separable quantum ...
Brandao, Fernando G. S. L. +1 more
core +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
From lifestyle to stimulation for dementia prevention in Brazil
The Lancet Regional Health. Americas, 2022 Timothy Daly
doaj +1 more source
Can All-Accuracy Accounts Justify Evidential Norms? [PDF]
, 2018 Some of the most interesting recent work in formal epistemology has focused on developing accuracy-based approaches to justifying Bayesian norms. These approaches are interesting not only because they offer new ways to justify these norms, but because ...
Meacham, Christopher J. G.
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