Results 71 to 80 of about 1,696,544 (312)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
, 2008 Norms affect political outcomes by shaping the strategies that political actors use to advance their interests. Norms do so by shaping the terms of the debates that underpin political decision making.
Dimitrakopoulos, Dionyssis G.
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
From lifestyle to stimulation for dementia prevention in Brazil
The Lancet Regional Health. Americas, 2022 Timothy Daly
doaj +1 more source
Social norms and economic incentives in firms
, 2003 This paper studies the interplay between economic incentives and social norms in firms. We introduce a general framework to model social norms arguing that norms stem from agents’ desire for, or peer pressure towards, social efficiency.
Huck, S., Weibull, J., Kubler, D.
core
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Apprendre à enseigner à l’école primaire. Une socialisation professionnelle paradoxale ?
Cahiers de la Recherche sur l'Education et les Savoirs, 2018 At the end of a long research integrating the contributions of many works, we analyze here the recurring evolution of the priorities for new teachers in primary school.
Stéphan Mierzejewski +3 more
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Social norms and optimal incentives in firms [PDF]
This paper deals with the interplay between economic incentives and social norms in firms. We outline a simple model of team production and provide preliminary results on linear incentive schemes in the presence of a social norm that may cause multiple ...
Kübler, Dorothea +2 more
core