Epidemiologic challenges in norovirus vaccine development
Human Vaccines & Immunotherapeutics, 2019 Norovirus is the leading cause of acute gastroenteritis (AGE) worldwide. In the United States norovirus is estimated to cause 19–21 million illnesses, 1.7–1.9 million outpatient visits, 56,000–71,000 hospitalizations, and 570–800 deaths annually. Through
Benjamin D. Hallowell +2 more
doaj +1 more source
Avaliação da ocorrência e decaimento de vírus entéricos e SARS-CoV-2 no tratamento de esgoto em reator UASB e da persistência de rotavírus A em lodo de UASB dessecado em leito de secagem [PDF]
, 2022 This research aimed to evaluate the occurrence of SARS-CoV-2, rotavirus A, and norovirus viruses in sewage, treated sewage, sludge and scum from a UASB reactor-type treatment system.
Antonio Natanael Costa Sancho
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Construction of Reverse Genetics System for Feline Calicivirus FCV‐BJ616 and Proteomic Analysis
MicrobiologyOpen, Volume 15, Issue 1, February 2026.This study successfully isolated the FCV‐BJ616 strain derived from cats and established a reverse genetics system. In vivo experiments showed that rFCV‐BJ616 exhibits wild‐type virulence, leading to high fever, weight loss, and multi‐organ lesions in infected cats. Proteomic analysis indicated that both rFCV‐BJ616 and FCV‐BJ616 share similar regulatory
Chunmei Xu +9 more
wiley +1 more source
Accelerate the Highly Efficient Development of mRNA Vaccines Through Advanced Computational Methods
MedComm, Volume 7, Issue 2, February 2026.This review explores the recent advancements in applying computational methods to optimize mRNA vaccines, with a primary focus on improvements in sequence design and delivery systems. ABSTRACT mRNA medicine is an emerging therapeutic approach that utilizes messenger RNA to synthesize functional proteins directly within target cells.
Ruichu Gu +5 more
wiley +1 more source
Bee products as alternatives in the treatment of viral infections
Journal of the Science of Food and Agriculture, Volume 106, Issue 1, Page 33-54, 15 January 2026.Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba +3 more
wiley +1 more source
Subprodutos e desperdícios da produção vinícola para a obtenção de nutracêuticos [PDF]
, 2016 Atualmente, a União Europeia encoraja o uso de subprodutos agro-alimentares como forma de obtenção de nutracêuticos, tais como proteínas, fibras, polissacarídeos, fitoquímicos, entre outros.
Ferreira da Vinha, Ana +3 more
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Beyond Pathology: α‐Synuclein Homeostasis and Three Principles to Guide Research
Movement Disorders Clinical Practice, EarlyView.
Alberto J. Espay, Andrew J. Lees
wiley +1 more source
Advanced Science, Volume 13, Issue 2, 9 January 2026.The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen +5 more
wiley +1 more source
Emergence of norovirus strains: A tale of two genes.
Virus Evolution, 2019 Noroviruses are a very diverse group of viruses that infect different mammalian species. In humans, norovirus is a major cause of acute gastroenteritis.
G. I. Parra
semanticscholar +1 more source
Cinco chaves para uma alimentação mais segura: manual [PDF]
, 2008 Versão em língua portuguesa do original publicado em inglês pela Organização Mundial da Saúde (OMS) em 2006, sob o título "Five Keys to Safer Food Manual".
Organização Mundial de Saúde
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