Results 41 to 50 of about 38,321 (206)

Norovirus and Other Viral Causes of Medically Attended Acute Gastroenteritis Across the Age Spectrum: Results from the MAAGE Study in the United States.

Clinical Infectious Diseases, 2021
BACKGROUND Acute gastroenteritis (AGE) causes a substantial burden in the United States, but its etiology frequently remains undetermined. Active surveillance within an integrated healthcare delivery system was used to estimate the prevalence and ...
R. Burke, Claire P. Mattison, Z. Marsh, Kayoko Shioda, Judy L. Donald, S. Salas, A. Naleway, Christianne Biggs, Mark A. Schmidt, A. Hall   +9 more
semanticscholar   +1 more source

High prevalence of GII norovirus in hospitalized children with acute diarrhea, in Beijing.

PLoS ONE, 2017
This study was addressed to the relationship between norovirus and acute diarrhea in hospitalized children, including hospital-acquired infection (HAI) and community-acquired infection (CAI) in a children's hospital in Beijing.
Liping Jia, You Zhang, Liying Liu, Huijin Dong, Linqing Zhao, Yuan Qian   +5 more
doaj   +1 more source

A narrative review of norovirus epidemiology, biology, and challenges to vaccine development

npj Vaccines
Norovirus is a leading cause of acute gastroenteritis (AGE) globally. AGE resulting from norovirus causes significant morbidity and mortality in countries of all income levels, particularly among young children and older adults.
Katherine B. Carlson, Anne Dilley, Thomas O’Grady, Jordan A. Johnson, B. Lopman, Emma Viscidi   +5 more
semanticscholar   +1 more source

Ultrasensitive Colorimetric Detection of Murine Norovirus Using NanoZyme Aptasensor.

Analytical Chemistry, 2019
Human norovirus (NoV) remains the most common cause of viral gastroenteritis and the leading cause of viral foodborne outbreaks globally. NoV is highly pathogenic with an estimated median viral infective dose (ID50) ranging from 18 to 1015 genome copies.
Pabudi Weerathunge, R. Ramanathan, V. Torok, Kate R. Hodgson, Yun Xu, R. Goodacre, B. Behera, V. Bansal   +7 more
semanticscholar   +1 more source

Global prevalence of norovirus gastroenteritis after emergence of the GII.4 Sydney 2012 variant: a systematic review and meta-analysis

Frontiers in Public Health
Introduction Norovirus is widely recognized as a leading cause of both sporadic cases and outbreaks of acute gastroenteritis (AGE) across all age groups.
Pan Zhang, Cai Hao, Xie Di, C. Xue, Jinsong Li, Guisen Zheng, Liu Hui, Zhaojun Duan   +7 more
semanticscholar   +1 more source

Identification of immune and viral correlates of norovirus protective immunity through comparative study of intra-cluster norovirus strains.

PLoS Pathogens, 2013
Whether or not primary norovirus infections induce protective immunity has become a controversial issue, potentially confounded by the comparison of data from genetically distinct norovirus strains.
Shu Zhu, Doron Regev, Makiko Watanabe, Danielle Hickman, Nissin Moussatche, Desyree Murta Jesus, Shannon M Kahan, Sawsan Napthine, Ian Brierley, Robert N Hunter, Divya Devabhaktuni, Melissa K Jones, Stephanie M Karst   +12 more
doaj   +1 more source

Persistence of Infectious Human Norovirus in Estuarine Water

Food and Environmnetal Virology
Norovirus is the predominant cause of viral acute gastroenteritis globally. While person-to-person is the most reported transmission route, norovirus is also associated with waterborne and foodborne illness, including from the consumption of contaminated
Daniel Rexin, A. Rachmadi, Joanne Hewitt
semanticscholar   +1 more source

Human norovirus targets enteroendocrine epithelial cells in the small intestine

Nature Communications, 2020
Human noroviruses are a major cause of diarrheal illness, but pathogenesis is poorly understood. Here, we investigate the cellular tropism of norovirus in specimens from four immunocompromised patients.
K. Green, S. Kaufman, Bianca M. Nagata, Natthawan Chaimongkol, Daniel Y. Kim, E. Levenson, C. Tin, Allison Behrle Yardley, Jordan A. Johnson, A. Barletta, K. Khan, N. Yazigi, S. Subramanian, Sangeetha R. Moturi, T. Fishbein, Ian N. Moore, S. Sosnovtsev   +16 more
semanticscholar   +1 more source

Impact of pH and protein hydrophobicity on norovirus inactivation by heat-denatured lysozyme.

PLoS ONE, 2020
Norovirus, the leading cause of non-bacterial food poisoning, is responsible for several outbreaks associated with bivalves and ready-to-eat food products worldwide.
Michiko Takahashi, Hajime Takahashi, Yumiko Okakura, Masahiro Ichikawa, Takashi Kuda, Bon Kimura   +5 more
doaj   +1 more source

Fucose Binding Cancels out Mechanical Differences between Distinct Human Noroviruses

Viruses, 2023
The majority of nonbacterial gastroenteritis in humans and livestock is caused by noroviruses. Like most RNA viruses, frequent mutations result in various norovirus variants.
Yuzhen Feng, Ronja Pogan, Lars Thiede, Jürgen Müller-Guhl, Charlotte Uetrecht, Wouter H. Roos   +5 more
doaj   +1 more source