Results 41 to 50 of about 72,116 (292)
Journal of General Virology, 2007 RNA recombination is a significant driving force in viral evolution. Increased awareness of recombination within the genusNorovirusof the familyCalicivirushas led to a rise in the identification of norovirus (NoV) recombinants and they are now reported at high frequency.
Bull, Rowena, Tanaka, Mark, White, Peter
openaire +3 more sources
Expression of Ifnlr1 on intestinal epithelial cells is critical to the antiviral effects of IFN-lambda against norovirus and reovirus [PDF]
, 2017 Lambda interferon (IFN-λ) has potent antiviral effects against multiple enteric viral pathogens, including norovirus and rotavirus, in both preventing and curing infection. Because the intestine includes a diverse array of cell types, however, the cell(s)
Baldridge, Megan T +7 more
core +2 more sources
Uirusu, 2020 Noroviruses commonly cause infectious gastroenteritis and massive food poisoning. There is an urgent need to elucidate the infection mechanism of noroviruses and to develop vaccines and therapeutic drugs. In addition to human disease, noroviruses have been implicated in animal disease.
openaire +3 more sources
New proof-of-concept in viral inactivation: virucidal efficacy of 405 nm light against feline calicivirus as a model for norovirus decontamination [PDF]
, 2016 The requirement for novel decontamination technologies for use in hospitals is ever present. One such system uses 405 nm visible light to inactivate microorganisms via ROS-generated oxidative damage.
Anderson, John G. +7 more
core +1 more source
Understanding Pediatric Norovirus Epidemiology: A Decade of Study among Ghanaian Children
Viruses, 2020 Understanding the epidemiology of human norovirus infection in children within Ghana and the entire sub-Saharan African region, where future norovirus vaccines would have the greatest impact, is essential.
Belinda L. Lartey +7 more
doaj +1 more source
Understanding the relationship between norovirus diversity and immunity
Gut microbes, 2021 Human noroviruses are the most common viral cause of acute gastroenteritis worldwide. Currently, there are no approved vaccines or specific therapeutics to treat the disease.
Lauren A Ford-Siltz +2 more
semanticscholar +1 more source
Genetic Analysis of Human Norovirus Strains in Japan in 2016–2017
Frontiers in Microbiology, 2018 In the 2016/2017 winter season in Japan, HuNoV GII.P16-GII.2 strains (2016 strains) emerged and caused large outbreaks of acute gastroenteritis. To better understand the outbreaks, we examined the molecular evolution of the VP1 gene and RdRp region in ...
Koo Nagasawa +20 more
semanticscholar +1 more source
High prevalence of GII norovirus in hospitalized children with acute diarrhea, in Beijing.
PLoS ONE, 2017 This study was addressed to the relationship between norovirus and acute diarrhea in hospitalized children, including hospital-acquired infection (HAI) and community-acquired infection (CAI) in a children's hospital in Beijing.
Liping Jia +5 more
doaj +1 more source
Clinical Infectious Diseases, 2021 BACKGROUND Acute gastroenteritis (AGE) causes a substantial burden in the United States, but its etiology frequently remains undetermined. Active surveillance within an integrated healthcare delivery system was used to estimate the prevalence and ...
R. Burke +9 more
semanticscholar +1 more source
Inhibition of cellular protein secretion by norwalk virus nonstructural protein p22 requires a mimic of an endoplasmic reticulum export signal. [PDF]
, 2013 Protein trafficking between the endoplasmic reticulum (ER) and Golgi apparatus is central to cellular homeostasis. ER export signals are utilized by a subset of proteins to rapidly exit the ER by direct uptake into COPII vesicles for transport to the ...
Crawford, Sue E. +4 more
core +2 more sources