Results 51 to 60 of about 26,875 (173)

Epidemiologic challenges in norovirus vaccine development

Human Vaccines & Immunotherapeutics, 2019
Norovirus is the leading cause of acute gastroenteritis (AGE) worldwide. In the United States norovirus is estimated to cause 19–21 million illnesses, 1.7–1.9 million outpatient visits, 56,000–71,000 hospitalizations, and 570–800 deaths annually. Through
Benjamin D. Hallowell, Umesh D. Parashar, Aron J. Hall   +2 more
doaj   +1 more source

Bridging the Gap Between General and Transplant Infectious Disease Practice

Transplant Infectious Disease, EarlyView.
ABSTRACT The population of iatrogenic immunocompromised individuals is steadily rising as we continue to improve in our ability to manage diseases, including cancer, autoimmune disease, and end‐organ dysfunction, with increasing access to novel agents and transplantation.
Jeremey Walker, Emily Eichenberger, Steven Pergam, Maricar Malinis, Andrea J. Zimmer   +4 more
wiley   +1 more source

Norovirus trends in British Columbia from 2021 to 2022: the relationship between wastewater surveillance and clinical outbreak data during the COVID-19 pandemic

Scientific Reports
Norovirus causes frequent global outbreaks and significant financial and operational burdens on healthcare systems. Albeit, norovirus is a non-notifiable disease in many jurisdictions.
Samantha Treagus, Jennifer Kopetzky, Christine Tchao, Tracy Chan, Farida Bishay, Hyo Jin Jeong, Daisy Yu, Angela Kong, Sarah C. Mansour, Natalie Prystajecky   +9 more
doaj   +1 more source

Early Prediction of Type‐Specific Influenza Incidence Using Wastewater‐Based Epidemiology

Water and Environment Journal, EarlyView.
We demonstrated that influenza incidence can be accurately predicted using viral RNA concentrations in wastewater. We also developed a method to separately estimate the incidence of influenza A and influenza B. Wastewater‐based estimates can theoretically detect epidemic trends approximately one week earlier than conventional case reporting, suggesting
Michio Murakami, Saeko Morikawa, Kaori Yamamoto, Yukino Yasuda, Hiroki Ando, Daisuke Motooka, Masaaki Kitajima, Naomi Sakon   +7 more
wiley   +1 more source

Preventing Foodborne Illness: Norovirus

EDIS, 2015
If you have ever had the stomach flu, norovirus was likely the culprit. Norovirus is the most common cause of foodborne illness in the United States and is transmitted through direct person-to-person contact or contaminated objects and food.
Rachael Silverberg, Melissa K. Jones, Renée Goodrich Schneider, Aswathy Sreedharan, Keith R. Schneider   +4 more
doaj   +1 more source

Coxsackievirus B Infections Are Associated With the Risk of Islet Autoimmunity in Children With Strong Genetic Susceptibility to Type 1 Diabetes—Results From the TRIGR Divia Study

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 6, September 2026.
ABSTRACT Aims Especially, the coxsackievirus B group of enteroviruses has been linked to the development of islet autoimmunity and type 1 diabetes in genetically susceptible individuals. Our aim was to study the possible associations of 10 different microbial infections with islet autoimmunity in a large international prospective study.
Maarit Oikarinen, Amirbabak Sioofy‐Khojine, Leena Puustinen, David Cuthbertson, Jussi Lehtonen, Niila V. V. Jouppila, Johnny Ludvigsson, Leena Hakola, Sari Niinistö, Iris Erlund, Mikael Knip, Jeffrey P. Krischer, Suvi M. Virtanen, Heikki Hyöty, on behalf of the TRIGR Investigators   +14 more
wiley   +1 more source

Multiplex PCR to Diagnose Gastrointestinal Infections: Key Limitations in Interpretation

United European Gastroenterology Journal, Volume 14, Issue 7, September 2026.
ABSTRACT Multiplex polymerase chain reaction (PCR) panels are increasingly used for the evaluation of acute diarrhea, providing rapid and sensitive detection of a broad range of enteric pathogens. However, their widespread adoption has created important interpretive challenges for clinicians.
Giannoula S. Tansarli, Ferric C. Fang
wiley   +1 more source

No evidence of an increase in the incidence of norovirus gastroenteritis hospitalizations in young children after the introduction of universal rotavirus immunization in Israel

Human Vaccines & Immunotherapeutics, 2019
Following the introduction of universal immunization against rotavirus, concerns were raised regarding pathogen-replacement of rotavirus by norovirus. The study aim was to examine the incidence and characteristics and norovirus gastroenteritis before and
Khitam Muhsen, Eias Kassem, Uri Rubenstein, Sophy Goren, Moshe Ephros, Lester M. Shulman, Dani Cohen   +6 more
doaj   +1 more source

Norovirus compared to other relevant etiologies of acute gastroenteritis among families from a semirural county in Chile

International Journal of Infectious Diseases, 2020
Objective: To determine the dynamics of norovirus disease, a major cause of acute gastroenteritis (AGE), compared to other relevant etiologies, among families living in a lower middle income area.
Yalda Lucero, Anne J. Lagomarcino, Mónica Espinoza, Nanami Kawakami, Nora Mamani, Nicole Huerta, Felipe Del Canto, Mauricio Farfán, Yoshihiro Sawaguchi, Sergio George, Miguel O’Ryan   +10 more
doaj   +1 more source

Treatment With Ruxolitinib and TAK‐779 Enhances GII.17 Human Norovirus Replication and Enables Serial Passaging in Human Intestinal Enteroids

Genes to Cells, Volume 31, Issue 5, September 2026.
We aimed to establish a simple method for GII.17 human norovirus (HuNoV) replication and serial passaging using wild‐type J2 human intestinal enteroids (HIEs). Treatment with ruxolitinib and TAK‐779, which target interferon and chemokine signaling, respectively, enhances viral replication and enables serial passaging of GII.17. ABSTRACT Human norovirus
Eri Hiraishi, Tsuyoshi Hayashi, Yoshiki Fujii, Hirokazu Kimura, Kosuke Murakami   +4 more
wiley   +1 more source