Results 41 to 50 of about 26,421 (155)

Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui, Elena N. Kitova, Ling Han, Lara K. Mahal, John S. Klassen   +4 more
wiley   +1 more source

Treosulfan–fludarabine conditioning in infants with severe combined immunodeficiencies: Extended study of the UK paediatric treosulfan study

British Journal of Haematology, EarlyView.
Summary Allogeneic haematopoietic stem cell transplantation (HSCT) is a curative therapy for severe combined immunodeficiency (SCID). Conditioning improves donor engraftment and freedom from immunoglobulin replacement (IgR) but increases the risks of acute and late toxicity. Treosulfan, a reduced toxicity alkylating agent, has emerged as an alternative
Su Han Lum, Sinéad Greener, Irum Latif Memon, Persis Amrolia, Zohreh Nademi, Robert Chiesa, Juliana Silva, Helen Young, Stephen Owens, Eleri Williams, Khuen Foong Ng, Terry Flood, Andrew R Gennery, Sophie Hambleton, Kanchan Rao, Mary Slatter   +15 more
wiley   +1 more source

Epidemiologic challenges in norovirus vaccine development

Human Vaccines & Immunotherapeutics, 2019
Norovirus is the leading cause of acute gastroenteritis (AGE) worldwide. In the United States norovirus is estimated to cause 19–21 million illnesses, 1.7–1.9 million outpatient visits, 56,000–71,000 hospitalizations, and 570–800 deaths annually. Through
Benjamin D. Hallowell, Umesh D. Parashar, Aron J. Hall   +2 more
doaj   +1 more source

Norovirus-induced Gastroparesis [PDF]

Cureus, 2019
Postviral gastroparesis can result from a variety of viral infections and may cause severe, persistent gastrointestinal symptoms. We report the case of an 85-year-old man with one year of persistent nausea, epigastric pain, early satiety, and 25-pound weight loss after an episode of viral gastroenteritis contracted on a cruise ship.
Sawin-Johnson, Kaylyn N, Packer, Clifford D   +1 more
openaire   +2 more sources

Life Course Malaria Exposure and SARS‐CoV‐2 Seroepidemiology in Ugandan Adolescents: A Longitudinal Study Nested in a Birth Cohort

Tropical Medicine &International Health, EarlyView.
ABSTRACT Background COVID‐19 has had major global health impacts, yet reported morbidity and mortality have been lower in Africa despite serological evidence of widespread infection. Malaria has been proposed as a potential modifier of susceptibility to and outcomes of SARS‐CoV‐2 infection.
Ludoviko Zirimenya, Doreen Nayebare, Claire Baine, Jacent Nassuuna, Milly Namutebi, Christopher Zziwa, Denis Nsubuga, Fred Kiwudhu, Florence Akello, Josephine Tumusiime, Gloria Oduru, Grace Kabami, Hellen Akurut, Rachel Nakyesige, Agnes Natukunda, Anne Wajja, Lawrence Lubyayi, Simon Kimuda, Gyaviira Nkurunungi, Jennifer Serwanga, Katie J. Doores, Emily L. Webb, Alison M. Elliott   +22 more
wiley   +1 more source

Specific Interactions between Human Norovirus and Environmental Matrices: Effects on the Virus Ecology

Viruses, 2019
Human norovirus is the major cause of non-bacterial epidemic gastroenteritis. Human norovirus binds to environmental solids via specific and non-specific interactions, and several specific receptors for human norovirus have been reported.
Mohan Amarasiri, Daisuke Sano
doaj   +1 more source

Unsuccessful treatment of chronic norovirus infection with enteral immunoglobulin in patients with common variable immunodeficiency, case report

IDCases, 2023
Background: Norovirus gastroenteritis is commonly an acute infection that lasts 2–3 days, but in immunocompromised patients norovirus can cause a chronic gastroenteritis lasting for years.
A.C.W. Christensen, C.H. Drabe, A. Loft, A.M. Lebech, T.L. Katzenstein   +4 more
doaj   +1 more source

NOROVIRUS-ASSOCIATED ENCEPHALOPATHY [PDF]

Pediatric Infectious Disease Journal, 2006
Norovirus is a common cause of gastroenteritis. We describe the case of a 23-month-old girl with encephalopathy possibly associated with norovirus infection. The viral genome was detected in stool, serum and cerebrospinal fluid (CSF) by reverse transcription polymerase chain reaction.
Shuichi, Ito, Saoko, Takeshita, Atsuo, Nezu, Yukoh, Aihara, Shuzo, Usuku, Yuzo, Noguchi, Shumpei, Yokota   +6 more
openaire   +2 more sources

Incidental Detection of Asymptomatic Colonic Anisakiasis During Surveillance Colonoscopy: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Anisakiasis is a parasitic infection caused by ingestion of raw or undercooked seafood containing Anisakis larvae. Although gastric involvement is common, colonic anisakiasis is rare and may be asymptomatic, making diagnosis difficult without endoscopic evaluation.
Masashi Omori, Kenta Shibahara, Takashi Murakami, Eiji Kamba, Kei Nomura, Hirofumi Fukushima, Dai Ishikawa, Mariko Hojo, Tomoyoshi Shibuya, Akihito Nagahara   +9 more
wiley   +1 more source

Norovirus trends in British Columbia from 2021 to 2022: the relationship between wastewater surveillance and clinical outbreak data during the COVID-19 pandemic

Scientific Reports
Norovirus causes frequent global outbreaks and significant financial and operational burdens on healthcare systems. Albeit, norovirus is a non-notifiable disease in many jurisdictions.
Samantha Treagus, Jennifer Kopetzky, Christine Tchao, Tracy Chan, Farida Bishay, Hyo Jin Jeong, Daisy Yu, Angela Kong, Sarah C. Mansour, Natalie Prystajecky   +9 more
doaj   +1 more source