Results 111 to 120 of about 16,047 (285)
Childhood morbidity and mortality of diarrhoeal diseases are high, particularly in low-income countries and noroviruses and sapoviruses are among the most frequent causes worldwide. Their epidemiology and diversity remain not well studied in many African
Aschalew Gelaw +3 more
semanticscholar +1 more source
CRISPR‐driven diagnostics: Molecular mechanisms, clinical efficacy and translational challenges
The CRISPR/Cas system has emerged as a transformative tool in the field of molecular diagnosis, offering unprecedented sensitivity, specificity and rapid detection capabilities. This review further examines the molecular mechanisms of CRISPR tools, compares their clinical efficacy with traditional methods and highlights cutting‐edge innovations such as
Zilong Wang +7 more
wiley +1 more source
Norovirus infection in immunocompromised hosts [PDF]
Acute gastroenteritis caused by noroviruses often has a duration of 2–0 days and is characteristically self-limiting. In contrast, chronic infection caused by noroviruses in immunocompromised individuals can last from weeks to years, making clinical ...
Direcció Tècnica d'Urbanisme +1 more
core +1 more source
Bacteroides fragilis employs bile salt hydrolase to reprogram host bile acid metabolism, generating lithocholic acid that directly blocks porcine deltacoronavirus infection by disrupting spike protein‐aminopeptidase N binding, defining a microbiota‐bile acid antiviral axis with therapeutic potential against coronaviruses.
Ya‐Qing Zhang +12 more
wiley +1 more source
Detection and quantification of classic and emerging viruses by skimmed-milk flocculation and PCR in river water from two geographical areas [PDF]
Molecular techniques and virus concentration methods have shown that previously unknown viruses are shed by humans and animals, and may be transmitted by sewage-contaminated water.
Bofill Mas, S. +7 more
core +1 more source
ABSTRACT Ion exchange chromatography (IEC) hyphenated to mass spectrometry (MS) is a powerful non‐denaturing technique used for analyzing protein charge heterogeneity (including posttranslational modifications such as deamidation, phosphorylation, and sialylation), as well as for characterizing complex protein mixtures. This review provides an overview
Ziran Zhai +3 more
wiley +1 more source
Noroviruses: State of the Art [PDF]
Noroviruses are a common cause of both endemic and epidemic gastroenteritis. These highly infectious viruses usually cause self-limited disease, but chronic infections occur in highly immunocompromised patients and unusual manifestations are also being described in some populations.
openaire +2 more sources
Human Monoclonal Antibodies That Neutralize Pandemic GII.4 Noroviruses.
BACKGROUND & AIMS Human noroviruses are responsible for approximately 200,000 deaths worldwide each year. In 2012, the GII.4 Sydney strain emerged and became the major circulating norovirus strain associated with human disease.
Gabriela Alvarado +6 more
semanticscholar +1 more source
Zebrafish as a Versatile Model Organism: From Tanks to Treatment
The zebrafish, with its optical transparency and genetic tractability, serves as a versatile in vivo platform for biomedical research. This review underscores its significance in modeling a wide spectrum of human diseases—from cancer to metabolic disorders—and in leveraging cutting‐edge technologies like CRISPR and TALENs.
Rupali Srivastava +9 more
wiley +1 more source
THE ETIOLOGIC SPECTRUM OF PATHOGENS OF VIRAL GASTROENTERITIS IN CHILDREN FROM BAKU
The article presents the results of research on the study of etiology, the logical structure of viral diarrhea in Baku (Azerbaijan) in 2015. It was found that more than half (62.6%), gastroenteritis in children of viral etiology, of which the leading ...
N. N. Aliev +4 more
doaj +1 more source

