Results 111 to 120 of about 16,047 (285)

Molecular detection and characterisation of sapoviruses and noroviruses in outpatient children with diarrhoea in Northwest Ethiopia

open access: yesEpidemiology and Infection, 2019
Childhood morbidity and mortality of diarrhoeal diseases are high, particularly in low-income countries and noroviruses and sapoviruses are among the most frequent causes worldwide. Their epidemiology and diversity remain not well studied in many African
Aschalew Gelaw   +3 more
semanticscholar   +1 more source

CRISPR‐driven diagnostics: Molecular mechanisms, clinical efficacy and translational challenges

open access: yesClinical and Translational Medicine, Volume 15, Issue 10, October 2025.
The CRISPR/Cas system has emerged as a transformative tool in the field of molecular diagnosis, offering unprecedented sensitivity, specificity and rapid detection capabilities. This review further examines the molecular mechanisms of CRISPR tools, compares their clinical efficacy with traditional methods and highlights cutting‐edge innovations such as
Zilong Wang   +7 more
wiley   +1 more source

Norovirus infection in immunocompromised hosts [PDF]

open access: yes, 2003
Acute gastroenteritis caused by noroviruses often has a duration of 2–0 days and is characteristically self-limiting. In contrast, chronic infection caused by noroviruses in immunocompromised individuals can last from weeks to years, making clinical ...
Direcció Tècnica d'Urbanisme   +1 more
core   +1 more source

A gut microbiota‐bile acid axis inhibits the infection of an emerging coronavirus by targeting its cellular receptor aminopeptidase N

open access: yesiMeta, Volume 4, Issue 5, October 2025.
Bacteroides fragilis employs bile salt hydrolase to reprogram host bile acid metabolism, generating lithocholic acid that directly blocks porcine deltacoronavirus infection by disrupting spike protein‐aminopeptidase N binding, defining a microbiota‐bile acid antiviral axis with therapeutic potential against coronaviruses.
Ya‐Qing Zhang   +12 more
wiley   +1 more source

Detection and quantification of classic and emerging viruses by skimmed-milk flocculation and PCR in river water from two geographical areas [PDF]

open access: yes, 2013
Molecular techniques and virus concentration methods have shown that previously unknown viruses are shed by humans and animals, and may be transmitted by sewage-contaminated water.
Bofill Mas, S.   +7 more
core   +1 more source

Developments in Ion Exchange Chromatography–Mass Spectrometry for the Characterization of Intact Proteins and Proteoforms

open access: yesJournal of Separation Science, Volume 48, Issue 9, September 2025.
ABSTRACT Ion exchange chromatography (IEC) hyphenated to mass spectrometry (MS) is a powerful non‐denaturing technique used for analyzing protein charge heterogeneity (including posttranslational modifications such as deamidation, phosphorylation, and sialylation), as well as for characterizing complex protein mixtures. This review provides an overview
Ziran Zhai   +3 more
wiley   +1 more source

Noroviruses: State of the Art [PDF]

open access: yesFood and Environmental Virology, 2010
Noroviruses are a common cause of both endemic and epidemic gastroenteritis. These highly infectious viruses usually cause self-limited disease, but chronic infections occur in highly immunocompromised patients and unusual manifestations are also being described in some populations.
openaire   +2 more sources

Human Monoclonal Antibodies That Neutralize Pandemic GII.4 Noroviruses.

open access: yesGastroenterology, 2018
BACKGROUND & AIMS Human noroviruses are responsible for approximately 200,000 deaths worldwide each year. In 2012, the GII.4 Sydney strain emerged and became the major circulating norovirus strain associated with human disease.
Gabriela Alvarado   +6 more
semanticscholar   +1 more source

Zebrafish as a Versatile Model Organism: From Tanks to Treatment

open access: yesMedComm – Future Medicine, Volume 4, Issue 3, September 2025.
The zebrafish, with its optical transparency and genetic tractability, serves as a versatile in vivo platform for biomedical research. This review underscores its significance in modeling a wide spectrum of human diseases—from cancer to metabolic disorders—and in leveraging cutting‐edge technologies like CRISPR and TALENs.
Rupali Srivastava   +9 more
wiley   +1 more source

THE ETIOLOGIC SPECTRUM OF PATHOGENS OF VIRAL GASTROENTERITIS IN CHILDREN FROM BAKU

open access: yesДетские инфекции (Москва), 2016
The article presents the results of research on the study of etiology, the logical structure of viral diarrhea in Baku (Azerbaijan) in 2015. It was found that more than half (62.6%), gastroenteritis in children of viral etiology, of which the leading ...
N. N. Aliev   +4 more
doaj   +1 more source

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