Results 131 to 140 of about 15,637 (259)

A single-amino-acid change in murine norovirus NS1/2 is sufficient for colonic tropism and persistence [PDF]

open access: yes, 2013
Human norovirus (HuNoV) is the major cause of acute nonbacterial gastroenteritis worldwide but has no clear animal reservoir. HuNoV can persist after the resolution of symptoms, and this persistence may be essential for viral maintenance within the ...
McCune, Broc T   +4 more
core   +2 more sources

A gut microbiota‐bile acid axis inhibits the infection of an emerging coronavirus by targeting its cellular receptor aminopeptidase N

open access: yesiMeta, Volume 4, Issue 5, October 2025.
Bacteroides fragilis employs bile salt hydrolase to reprogram host bile acid metabolism, generating lithocholic acid that directly blocks porcine deltacoronavirus infection by disrupting spike protein‐aminopeptidase N binding, defining a microbiota‐bile acid antiviral axis with therapeutic potential against coronaviruses.
Ya‐Qing Zhang   +12 more
wiley   +1 more source

Persistent enteric murine norovirus infection is associated with functionally suboptimal virus-specific CD8 T cell responses [PDF]

open access: yes, 2013
Norovirus (NV) gastroenteritis is a major contributor to global morbidity and mortality, yet little is known about immune mechanisms leading to NV control. Previous studies using the murine norovirus (MNV) model have established a key role for T cells in
Artis, David   +8 more
core   +2 more sources

Human Noroviruses in Swine and Cattle

open access: yesEmerging Infectious Diseases, 2007
Human noroviruses are the predominant cause of foodborne gastroenteritis worldwide. Strains of norovirus also exist that are uniquely associated with animals; their contribution to the incidence of human illness remains unclear. We tested animal fecal samples and identified GIII (bovine), GII.18 (swine), and GII.4 (human) norovirus sequences ...
Kirsten Mattison   +7 more
openaire   +3 more sources

Tulane virus protease as a structural surrogate for inhibitor screening of human norovirus proteases

open access: yesJournal of Virology
Human norovirus (HuNoV) is a significant cause of gastroenteritis worldwide, affecting people of all age groups. There are currently no vaccines or drugs available, leaving susceptible populations vulnerable to severe or protracted illness.
Son Pham   +6 more
doaj   +1 more source

First report of a norovirus outbreak associated with the variant Sydney 2012 in Portugal [PDF]

open access: yes, 2014
Introduction: This study describes the investigation of a gastroenteritis outbreak in a group of students, associated with a dinner reunion in February 2013 in Porto, Portugal. Methodology: An anonymous structured questionnaire was developed and sent to
Conceição-Neto, N.   +4 more
core   +2 more sources

Natural Norovirus Infections in Rhesus Macaques

open access: yesEmerging Infectious Diseases, 2016
Using a recently developed real-time reverse transcription PCR, I retested 500 fecal samples from rhesus macaques collected in 2008. Previous conventional reverse transcription PCR testing identified 1 isolate of GII norovirus; retesting found GI, GII ...
Tibor Farkas
doaj   +1 more source

Epidemiological and virological investigation of a Norovirus outbreak in a resort in Puglia, Italy [PDF]

open access: yes, 2007
Background: This paper describes the third large outbreak of Norovirus (NoV) gastroenteritis reported in the Southern Italy region of Puglia. Methods: A matched case control study was conducted, on 19 July 2005, for investigating risk factors, using a
Caterina Rizzo   +37 more
core   +2 more sources

Development of a Recombinase Polymerase Amplification Assay for Detection of Epidemic Human Noroviruses

open access: yesScientific Reports, 2017
Human norovirus is a leading cause of viral gastroenteritis worldwide. Rapid detection could facilitate control, however widespread point-of-care testing is infrequently done due to the lack of robust and portable methods.
M. Moore, L. Jaykus
semanticscholar   +1 more source

Hospitalization due to norovirus and genotypes of rotavirus in pediatric patients, state of Espírito Santo

open access: yesMemorias do Instituto Oswaldo Cruz, 2008
Viruses are the leading cause for hospitalization due to gastroenteritis worldwide. Group A rotaviruses (RV) are the most prevalent and are assorted in glycoproteins (G) and protease sensitive (P) dual genotypes based on polymorphic genes that encode the
Leandro Rua Ribeiro   +6 more
doaj   +1 more source

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