Results 111 to 120 of about 2,924,837 (312)

Labor Relations Law in North America [PDF]

open access: yes, 2000
[Excerpt] In establishing their Agreement on Labor Cooperation as a complement to the North American Free Trade Agreement, the governments of Canada, the United States and Mexico accepted the fact that each nation had evolved a different system of labor ...
Banks, Kevin   +3 more
core   +1 more source

North American Species of the Genus Axonopsis (Acarina: Aturidae: Axonopsinae) [PDF]

open access: yes, 2017
(excerpt) Members of the genus Axonopsis have a broad zoogeographic distribution but are unreported from the Australian region and South America south of Colombia.
Cook, David R
core   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Matching estimators of causal effects in clustered observational studies

open access: yesJournal of Causal Inference
Marine conservation preserves fish biodiversity, protects marine and coastal ecosystems, and supports climate resilience and adaptation. Despite the importance of establishing marine protected areas (MPAs), research on the effectiveness of MPAs with ...
Cui Can   +4 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Cory thalia canosa (Araneae: Salticidae) reassigned to Anasaitis [PDF]

open access: yes, 1999
Four species of Cory thalia C.L.Koch 1851 were reported by Richman & Cutler (1978) to occur in North America north of Mexico. Subsequently, one of these four species, C.
Edwards, G. B.
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

INDIGENOUS LAND TENURE AND LAND USE IN ALASKA: COMMUNITY IMPACTS OF THE ALASKA NATIVE CLAIMS SETTLEMENT ACT [PDF]

open access: yes
Through the utilization of qualitative methods such as archival analysis, semi-structured interviewing, comparative and extended case studies, and observation, this paper closely examines two related Alaska Native communities.
Hirsch, Brian H., Jacobs, Harvey M.
core   +1 more source

Sports industry research North America: USA & Canada [PDF]

open access: yes, 2019
The Sports Industry is a potential business that not only involves the game at the field. It includes different aspects like food & beverage, apparel, sponsorship, licensing, events, tourism, and infrastructure (ATKearney, 2011).
Dezsenyi, Daniel   +2 more
core  

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