Results 141 to 150 of about 479,956 (265)

How genetic counselors in North America describe their professional identity. [PDF]

J Genet Couns
Schwartz L, Stenberg K, Casey A, Fitzpatrick J, Mackall MS, Goodenberger ML, Arjunan A, Witherington S, Kalia I, Mills R.   +9 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

A weakened diurnal weather constraint leads to longer burning hours in North America. [PDF]

Sci Adv
Luo K, Wang X, Castellanos-Acuna D, Flannigan M.   +3 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

IL12RB1 Deficiency Appearing in North America: Expanding the Clinical Phenotypes. [PDF]

Clin Infect Dis
Wang C, Marciano BE, Harris AJ, Johnston AM, Apaydin Arikan E, Bayer DK, Solomon BD, Price NB, Platt CD, Modi AJ, Shaker MS, Seroogy CM, Johnson D, Kleiner DE, Chirombo Kluczynski L, Anderson VL, Daub JR, Berghout J, Oler AJ, Walkiewicz MA, Similuk M, Lewis DB, Galgiani JN, Freeman AF, Rosen LB, Hsu AP, Zerbe CS, Holland SM.   +27 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Development of a Patient Journey Map for Metabolic Dysfunction-Associated Steatohepatitis: A Comprehensive Assessment of the Patient Journey in North America. [PDF]

J Patient Exp
Garcia DO, Calle RA, Seth A, Norton TD, Lederer DJ, Richardson A, Berg J, Betel M, Chang H, Daniels H, Eskridge W, McIntyre J, Villiotti Madison G, Villiotti T, Sellati R.   +14 more
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Exploring Afghan Refugees' Post-Resettlement Experiences in North America: A Scoping Review. [PDF]

Can J Nurs Res
Amanzai H, Wang BQ, Catallo C, Guruge S, Sidani S, Sethi B, Ziegler E, Nishi S, Joy P, Stafford A, Borges A, Sediq M.   +11 more
europepmc   +1 more source

Water for North America [PDF]

Science, 1965
openaire   +2 more sources