Results 101 to 110 of about 319,839 (313)

In Vivo CRISPR Screening Identifies the Glutamate Receptor GRIA2 as Promoting Peritoneal Metastasis of Gastric Cancer via Calcium‐Dependent β‐Catenin Activation

open access: yesAdvanced Science, EarlyView.
We identified GRIA2 as a critical driver of gastric cancer peritoneal metastasis through in vivo CRISPR screening. Mechanistically, GRIA2‐mediated calcium influx inhibits GSK3β and activates Wnt/β‐catenin signaling, driven by glutamate from cancer‐associated fibroblasts.
Jie Sun   +13 more
wiley   +1 more source

The Sustainable Energy and Economy Development in Northeast China

open access: yesChemical Engineering Transactions, 2015
With the rapid economic development, the conflicts between energy and economy development gradually emerge. The economic development in Northeast China heavily rely on energy consumption for a long time, to find a more sustainable way for energy and economy development of northeast china, this paper establishes a economic analysis model, this model has
openaire   +2 more sources

A currency union or an exchange rate union: evidence from Northeast Asia [PDF]

open access: yes
This paper examines whether or not Northeast Asia economies, namely, China, Japan, Korea, and Taiwan, can form a currency union, where a single currency and a uniform monetary policy are adopted, or an exchange rate union where all the currencies are ...
Jeon, Bang Nam, Zhang, Hongfang
core   +1 more source

Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis

open access: yesAdvanced Science, EarlyView.
This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun   +15 more
wiley   +1 more source

LAND TENURE INSECURITY AND LABOR ALLOCATION IN RURAL CHINA [PDF]

open access: yes
Farmers' ability to leave agriculture is an important and debated topic in China and other countries. Many scholars believe China's unique land tenure policies prevent farmers from leaving agriculture. This paper examines the hypothesis that China's land
Lohmar, Bryan
core   +1 more source

Faune malacologique terrestre des Iles Paracels [PDF]

open access: yes, 1958
The author presents a study on the land shells of the Paracel Islands, group of islands, reefs, banks and other maritime features in the South China Sea.
Saurin, Edmond
core  

Mapping the “Supply–Demand–Flow” of Ecosystem Services for Ecosystem Management in China

open access: yesAdvanced Science, EarlyView.
This study develops a “supply–demand–flow” framework clarifies how ecosystem services move between regions by distinguishing potential and actual supply and demand. Using integrated biophysical–socioeconomic modeling, nine services in China were mapped.
Yikun Zhang   +3 more
wiley   +1 more source

An Intercomparison between ERA-Interim Reanalysis and Observed Precipitation in Northeast China

open access: yesDiscrete Dynamics in Nature and Society, 2015
Recently, the European Center for Medium-Range Weather Forecasts (ECMWF) released a new set of reanalysis data—ERA-Interim. We make an intercomparison between ERA-Interim precipitation and observed precipitation in Northeast China. The results show that,
Jie Zhou, Junhu Zhao
doaj   +1 more source

Large‐Scale Genomics Reveals Three‐Source Ancestry and Layered Adaptation to High Altitude in Tibetan Chickens

open access: yesAdvanced Science, EarlyView.
Whole‐genome analysis of 1,054 chickens reveals three ancestral sources (NWC, SYA, and SHF) with distinct temporal entry patterns into the Tibetan Plateau. Route‐specific selection scans, calibrated against a demographic null, suggest complementary functional enrichments—vascular homeostasis (NWC), calcium signaling and cardiac adaptation (SYA), and ...
Zongyi Zhao   +7 more
wiley   +1 more source

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